Basal insulin therapy in type 2 diabetes

MA Bethel, MN Feinglos - The Journal of the American Board …, 2005 - Am Board Family Med
Patients with type 2 diabetes mellitus are usually treated initially with oral antidiabetic
agents, but as the disease progresses, most patients eventually require insulin to maintain …

Is there a need for a better basal insulin?

R Guthrie - Clinical diabetes, 2001 - go.gale.com
Basal insulin therapy is an integral part of intensive management of type 1 diabetes and is
often used in conjunction with oral agent therapy for type 2 diabetes. Currently available …

Basal insulin: physiology, pharmacology, and clinical implications

KD Niswender - Postgraduate medicine, 2011 - Taylor & Francis
Primary goals in the treatment of type 2 diabetes mellitus (T2DM) include lowering blood
glucose levels sufficiently to prevent micro-and macrovascular complications while limiting …

The role of basal insulin therapy in patients with type 2 diabetes mellitus

V Fonseca - Insulin, 2006 - Elsevier
BACKGROUND:: The natural course of type 2 diabetes mellitus (DM) is characterized by
insulin resistance followed by a progressive decline in β-cell function, which results in …

Insulin therapy in patients with type 2 diabetes mellitus: Treatment to target fasting and postprandial blood glucose levels

D Raccah - Insulin, 2006 - Elsevier
BACKGROUND:: Type 2 diabetes mellitus (DM) is a progressive disease characterized by
both insulin resistance and β-cell failure, resulting in a decline in insulin secretion and …

Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin

J Rosenstock, SL Schwartz, CM Clark Jr… - Diabetes …, 2001 - Am Diabetes Assoc
OBJECTIVE—To determine the safety and efficacy of the long-acting analog insulin glargine
compared with NPH insulin in patients with type 2 diabetes who were previously treated with …

Initiating basal insulin therapy in type 2 diabetes: practical steps to optimize glycemic control

A Philis-Tsimikas - The American journal of medicine, 2013 - Elsevier
Primary care practitioners are increasingly responsible for the management of the escalating
numbers of patients with type 2 diabetes. The majority of these patients will require insulin …

Review of basal‐plus insulin regimen options for simpler insulin intensification in people with type 2 diabetes mellitus

D Raccah, D Huet, A Dib, F Joseph… - Diabetic …, 2017 - Wiley Online Library
Aims To identify simple insulin regimens for people with Type 2 diabetes mellitus that can be
accepted and implemented earlier in primary and specialist care, taking into consideration …

Timely initiation of basal insulin

MC Riddle - The American journal of medicine, 2004 - Elsevier
Recognition of the basal and postprandial components of hyperglycemia, in tandem with the
development of new insulins and other clinical research, has led to a reassessment of type 2 …

Insulin treatment in type 1 diabetes

GB Bolli - Endocrine Practice, 2006 - Elsevier
Objective To present key aspects and strategies for use of insulin therapy in patients with
type 1 diabetes mellitus. Methods Limitations and advantages of various insulin regimens …