Abnormally low hemoglobin A1c as harbinger of hemoglobinopathy

JS Louis, A Valdini - The Journal of the American Board of …, 2019 - Am Board Family Med
Hemoglobin A1c is frequently used in primary care to screen for and monitor disorders of
glucose metabolism. A number of clinical syndromes may impact the accuracy of this …

Effect of hemoglobinopathies on hemoglobin A1c measurements

CL Malekiani, A Ganesan, CF Decker - The American journal of …, 2008 - amjmed.com
The measurement of glycosolated hemoglobin (HbA1c) is accepted widely as the
cornerstone of the management of diabetes. Recently, a new information campaign and …

Interference With Hemoglobin A1c Determination by the Hemoglobin Variant Shelby

RT Scuderi, TL Griffin, SP Mehta… - American journal of …, 2007 - academic.oup.com
Hemoglobin variant carrier status was found in a 46-year-old African American man
following detection of a falsely elevated hemoglobin A1c (HbA1c) by ion-exchange high …

Spurious elevation of hemoglobin A1c by hereditary persistence of fetal hemoglobin.

LE Egede, E Obah, T Lorch, T Oussova - Southern medical journal, 2000 - europepmc.org
We present the case of a 61-year-old black woman with a diagnosis of type 2 diabetes and a
falsely elevated hemoglobin A1c (HbA1c) due to hereditary persistence of fetal hemoglobin …

Hemoglobin a1C — Infatuation or the Real Thing?

DM Nathan - New England Journal of Medicine, 1990 - Mass Medical Soc
The clinician's romance with newly introduced tests in medicine follows a predictable
course. Initially greeted with unfettered enthusiasm, the tests are subjected to further scrutiny …

Inaccurate hemoglobin A1C levels in patients with type 1 diabetes and hereditary persistence of hemoglobin F

EI Felner, M McGrath - The Journal of pediatrics, 2008 - Elsevier
We report 2 African-American boys with type 1 diabetes and hereditary persistence of
hemoglobin F. The diagnosis came to light after both patients exhibited inconsistent …

Evaluation of a Fully Automated High-Performance Liquid Chromatography Assay for Hemoglobin A1c

HM Khuu, CA Robinson, K Goolsby… - … of Pathology and …, 1999 - meridian.allenpress.com
Introduction.—Measurement of hemoglobin A1c (HbA1c) is used as an objective measure of
long-term blood glucose control in diabetic patients. Recent improvements in automation …

False elevation of hemoglobin A1 by hereditary persistence of fetal hemoglobin.

DL Vesely, LL Sanders - Journal of medicine, 1987 - europepmc.org
Measurement of glycosylated hemoglobin (HgA1) is frequently helpful in the management of
patients with diabetes mellitus as it provides an index of average glucose control over the …

HbA1c does not always estimate average glucose

KJ Behan, J Merschen - American Society for Clinical …, 2011 - clsjournal.ascls.org
Hemoglobin A1c (HbA1c) testing can be inaccurate in persons with elevated amounts of
Hemoglobin F, or with abnormal hemoglobins found in sickle cell trait, HbC trait and HbE …

A Rare Hemoglobin Variant (β51Pro → His) Causing Misleading Measurements of Hemoglobin A1c

MP Mackley, A Morgenthau, M Elnenaei… - Journal of the …, 2022 - academic.oup.com
Glycated hemoglobin A1c (HbA1c) is considered the standard of care for the testing and
monitoring of diabetes. Its ability to accurately reflect glycemia, however, is imperfect …