With the increasing incidence of acquired immunodeficiency syndrome (AIDS) in the United
States, family physicians and other primary care specialists will provide health care for a …

It is postulated that the unstable hydroxylamine metabolite of sulphamethoxazole is
responsible for the adverse reactions to co-trimoxazole and in HIV infection systemic …

The relationship between the onset of adverse events to cotrimoxazole in HIV-infected
patients and the subsequent development of toxoplasmosis, other AIDS-defining events and …

In response to the article by Kelly et al.(Clinical Infectious Diseases (1992) 14, 1034-1039),
a further case of severe reaction to trimethoprim-sulfamethoxazole (TMP-SMZ) is reported. A …

The case is reported of a 30-year-old HIV positive man in Maryland, USA, who suffered a life-
threatening reaction to trimethoprim-sulfamethoxazole (TMP-SMZ) prophylaxis against …

Trimethoprim-sulfamethoxazole is an important medication for the treatment and prevention
ofPneumocystis cariniipneumonia in patients with the acquired immunodeficiency …

1 M 33< 10 8400 PCP treatment 960 Rash, fever Anaphylaxis, rash, fever, periorbital
oedema 2 M 25< 10 8400 PCP treatment 960 Nausea, fever Rash, fever 3 M 46< 50 8400 …

The clinical features of three patients with a life-threatening reaction to trimethoprim-
sulfamethoxazole (TMP-SMZ) are presented along with seven other cases from the …

The origin of the increased frequency of side-effects to co-trimoxazole in HIV-positive
patients is unknown. Data on plasma concentrations of the parent compounds are …

The treatment of Pneumocystis carinii pneumonia (PCP) with high-dose of co-trimoxazole
has been reported to cause adverse reactions at higher frequencies (27-64%) in patients …