[HTML][HTML] Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

GEN-1 immunotherapy for the treatment of ovarian cancer

PH Thaker, N Borys, J Fewell, K Anwer - Future Oncology, 2019 - Future Medicine
GEN-1 is a gene-based immunotherapy, comprising a human IL-12 gene expression
plasmid and a synthetic plasmid delivery system, delivered intraperitoneally (ip.) to produce …

Multiple autoimmune side effects of immune checkpoint inhibitors in a patient with metastatic melanoma receiving pembrolizumab

N Kethireddy, S Thomas, P Bindal… - Journal of Oncology …, 2021 - journals.sagepub.com
Introduction Immune agents including anti-programmed death receptor-1 and anti-cytotoxic
T-lymphocyte antigen-4 have been associated with numerous immune-related …

Acute cytokine release syndrome after a first dose of pembrolizumab as second-line treatment for metastatic, programmed death-ligand 1-positive, non-small-cell lung …

CV Normand, HO Zender, DM Staehli… - Journal of Oncology …, 2021 - journals.sagepub.com
Introduction The use of programmed death-ligand 1 (PD-L1) checkpoint inhibitor therapy is
expanding, although its adverse effects are not completely known. We report on a rare case …

The potpourri of family medicine, in sickness and in health

MA Bowman, AV Neale… - The Journal of the …, 2018 - Am Board Family Med
Some aspects of the health of Americans are declining, and family medicine is addressing
these ailments. Obesity is one factor, and family physicians provide nutrition counseling …

Body's Own Epitopes among Foreign Ones: T Cells and Autoantigens

ES Shilov - Molecular Biology, 2019 - Springer
T cells play a key role in adaptive immunity reactions, recognizing antigens using variable
TCRs. Functional TCR subunit genes are formed by somatic rearrangement, and some of …

[PDF][PDF] Cancer immunotherapy: The way to the nobel prize in medicine

N Rezaei, E Rayzan - Acta Medica Iranica, 2018 - acta.tums.ac.ir
On 2018, the Nobel prize in physiology and medicine has been awarded jointly to two
immunologists. They were working on the immune checkpoint inhibitors which their research …

Свой эпитоп среди чужих–Т-клетки и аутоантигены

ЕС Шилов - Молекулярная биология, 2019 - elibrary.ru
Т-лимфоциты играют ключевую роль в реакциях адаптивного иммунитета, распознавая
антигены при помощи вариабельных T-клеточных рецепторов (TCR). Функциональные …