Colorectal cancer is the second leading cause of cancer-related death in Europe and the
United States. Survival is strongly related to stage at diagnosis and population-based …

Colorectal cancer incidence and mortality in patients younger than 50 years are increasing,
but screening before the age of 50 is not offered in Europe. Advanced-stage diagnosis and …

Objective: As part of the second phase of the North American Prodrome Longitudinal Study
(NAPLS-2), Cannon and colleagues report, concurrently with the present article, on a risk …

Importance Early identification of individuals at high risk for the onset of bipolar spectrum
disorder (BPSD) is key from both a clinical and research perspective. While previous work …

OBJECTIVES: A systematic review and meta-analysis was performed to summarize the
available evidence on risk scores for predicting advanced colorectal neoplasia (advanced …

Background Nutrition and lifestyle have been long established as risk factors for colorectal
cancer (CRC). Modifiable lifestyle behaviours bear potential to minimize long-term CRC risk; …

Colorectal cancer screening reduces colorectal cancer incidence and mortality. Risk models
based on phenotypic variables have relatively good discrimination in external validation and …

Objective Youth with subthreshold mania are at increased risk of conversion to bipolar
disorder (BP) I/II. Predictors for conversion have been published for the group as a whole …

Background: This study aimed to compare and externally validate risk scores developed to
predict incident colorectal cancer (CRC) that include variables routinely available or easily …

Background Laparoscopic sleeve gastrectomy (LSG) is rapidly gaining popularity.
Estimating the risk of postoperative adverse events can improve surgical decision-making …