[HTML][HTML] Real-world outcomes in patients with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor inhibitors

H Mehta, A Tufail, V Daien, AY Lee, V Nguyen… - Progress in retinal and …, 2018 - Elsevier
Clinical trials identified intravitreal vascular endothelial growth factor inhibitors (anti-VEGF
agents) have the potential to stabilise or even improve visual acuity outcomes in …

[HTML][HTML] Oxidative stress in retinal pigment epithelium degeneration: From pathogenesis to therapeutic targets in dry age-related macular degeneration

M Maurya, K Bora, AK Blomfield… - Neural regeneration …, 2023 - journals.lww.com
Age-related macular degeneration is a primary cause of blindness in the older adult
population. Past decades of research in the pathophysiology of the disease have resulted in …

Fully automated detection of retinal disorders by image-based deep learning

F Li, H Chen, Z Liu, X Zhang, Z Wu - Graefe's Archive for Clinical and …, 2019 - Springer
Purpose With the aging population and the global diabetes epidemic, the prevalence of age-
related macular degeneration (AMD) and diabetic macular edema (DME) diseases which …

On OCT image classification via deep learning

D Wang, L Wang - IEEE Photonics Journal, 2019 - ieeexplore.ieee.org
Computer-aided diagnosis of retinopathy is a research hotspot in the field of medical image
classification. Diabetic macular edema (DME) and age-related macular degeneration (AMD) …

Projection artifact removal improves visualization and quantitation of macular neovascularization imaged by optical coherence tomography angiography

Q Zhang, A Zhang, CS Lee, AY Lee, KA Rezaei… - Ophthalmology …, 2017 - Elsevier
Purpose To visualize and quantify the size and vessel density of macular neovascularization
(MNV) using optical coherence tomography angiography (OCTA) with a projection artifact …

[HTML][HTML] Not all stressors are equal: Mechanism of stressors on RPE cell degeneration

Y Tong, S Wang - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Age-related macular degeneration (AMD) is a major cause of irreversible blindness among
the elderly population. Dysfunction and degeneration of the retinal pigment epithelial (RPE) …

[HTML][HTML] Age-related macular degeneration: genetic and environmental factors of disease

Y Chen, M Bedell, K Zhang - Molecular interventions, 2010 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is the most common cause of visual impairment
among the elderly in developed countries, and its prevalence is thus increasing as the …

[PDF][PDF] Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration

SK Iyengar, D Song, BEK Klein, R Klein… - The American Journal of …, 2004 - cell.com
To examine the genetic basis of age-related macular degeneration (ARMD), a degenerative
disease of the retinal pigment epithelium and neurosensory retina, we conducted a …

[HTML][HTML] Risk factors for age-related macular degeneration: findings from the Andhra Pradesh eye disease study in South India

S Krishnaiah, T Das, PK Nirmalan… - … & visual science, 2005 - iovs.arvojournals.org
purpose. To assess prevalence, potential risk factors, and population attributable risk
percentage (PAR%) for age-related macular degeneration (AMD) in the Indian state of …

[HTML][HTML] Plasma metabolomics of intermediate and neovascular age-related macular degeneration patients

SL Mitchell, C Ma, WK Scott, A Agarwal… - Cells, 2021 - mdpi.com
To characterize metabolites and metabolic pathways altered in intermediate and
neovascular age-related macular degeneration (IAMD and NVAMD), high resolution …