[HTML][HTML] Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism
…, PT Liu, D Kiken, YR Helfrich… - The Journal of …, 2007 - Am Soc Clin Investig
An essential element of the innate immune response to injury is the capacity to recognize
microbial invasion and stimulate production of antimicrobial peptides. We investigated how this …
microbial invasion and stimulate production of antimicrobial peptides. We investigated how this …
Treatment of acne in pregnancy
…, B Rainer, DL Sachs, YR Helfrich - The Journal of the …, 2016 - Am Board Family Med
Acne vulgaris is a common disease of the pilosebaceous unit and affects adolescents and
adults. Because high-quality guidelines regarding treatment of acne in pregnancy are scarce, …
adults. Because high-quality guidelines regarding treatment of acne in pregnancy are scarce, …
Clinical, histologic, and molecular analysis of differences between erythematotelangiectatic rosacea and telangiectatic photoaging
YR Helfrich, LE Maier, Y Cui, GJ Fisher… - JAMA …, 2015 - jamanetwork.com
Importance Facial erythema and telangiectasia are commonly associated with the
erythematotelangiectatic subtype of rosacea (ETR). It is important for clinicians to recognize that …
erythematotelangiectatic subtype of rosacea (ETR). It is important for clinicians to recognize that …
A randomized, controlled, split-face clinical trial of 1320-nm Nd: YAG laser therapy in the treatment of acne vulgaris
…, DL Sachs, DJ Karimipour, YR Helfrich… - Journal of the American …, 2007 - Elsevier
BACKGROUND: There is a need for additional effective treatments for acne vulgaris. Laser
therapy has been explored as a therapeutic option for acne, but rigorously designed studies …
therapy has been explored as a therapeutic option for acne, but rigorously designed studies …
Effect of smoking on aging of photoprotected skin: evidence gathered using a new photonumeric scale
YR Helfrich, L Yu, A Ofori, TA Hamilton… - Archives of …, 2007 - jamanetwork.com
Objectives To develop a reproducible photonumeric scale to assess photoprotected skin
aging and to determine whether health and lifestyle factors, such as smoking, affect skin aging …
aging and to determine whether health and lifestyle factors, such as smoking, affect skin aging …
[HTML][HTML] Mutations in PERP cause dominant and recessive keratoderma
…, LM Milstone, V Gildenstern, YR Helfrich… - Journal of Investigative …, 2019 - Elsevier
Investigation of genetic determinants of Mendelian skin disorders has substantially advanced
understanding of epidermal biology. Here we show that mutations in PERP, encoding a …
understanding of epidermal biology. Here we show that mutations in PERP, encoding a …
[PDF][PDF] The malignancy potential of porokeratosis: a single-center retrospective study
T Novice, M Nakamura, Y Helfrich, YR Helfrich - Cureus, 2021 - cureus.com
Background Porokeratosis (PK) is a rare group of keratinization disorders. While the overall
prognosis of PK is favorable, malignant transformation of PK to skin cancer has been …
prognosis of PK is favorable, malignant transformation of PK to skin cancer has been …
[HTML][HTML] A qualitative comparison of symptoms and impact of varying stages of basal cell carcinoma
…, EN Bush, ALS Chang, ST Arron, YR Helfrich… - Dermatology and …, 2015 - Springer
Introduction Basal cell carcinoma (BCC) is the most common form of skin cancer; however,
few data are available relating to patients’ perspectives and experiences of this disease. This …
few data are available relating to patients’ perspectives and experiences of this disease. This …
Patient interest in and familiarity with anti‐aging therapies: A survey of the general dermatology clinic population
…, HA Chubb, DL Sachs, YR Helfrich - Journal of Cosmetic …, 2018 - Wiley Online Library
Background The appearance of aging skin is a common complaint among dermatology
patients. There is an expanding market for anti‐aging therapies, but little information is available …
patients. There is an expanding market for anti‐aging therapies, but little information is available …
Topical becocalcidiol for the treatment of psoriasis vulgaris: a randomized, placebo‐controlled, double‐blind, multicentre study
YR Helfrich, S Kang, TA Hamilton… - British Journal of …, 2007 - academic.oup.com
Background Becocalcidiol is a vitamin D 3 analogue which has not caused hypercalcaemia
or significant irritation in preclinical trials. Objectives To evaluate the efficacy and safety of …
or significant irritation in preclinical trials. Objectives To evaluate the efficacy and safety of …