Astrict glycemic control reduces the risk of the development of microand macrovascular
complications (1–3). In the UK Prospective Diabetes Study, each 1% reduction in HbA1c was …

Background The Four-Dimensional Symptom Questionnaire (4DSQ) is a self-report questionnaire
that has been developed in primary care to distinguish non-specific general distress …

Background. Postherpetic neuralgia (PHN) is a frequent complication of herpes zoster (HZ).
Treatment results of this severe and long-lasting pain syndrome are often disappointing. …

OBJECTIVE: To assess the association of decline in physical functioning with number of
chronic diseases and with specific comorbidity in different index diseases. METHODS: A …

Objective To compare the effects of a minimal intervention strategy aimed at assessment
and modification of psychosocial prognostic factors and usual care for treatment of (sub)acute …

BACKGROUND: Old people (75+) are underrepresented in studies on the prevalence of
and risk factors for depression while the number of elderly people suffering from this mood …

OBJECTIVE: The aim of this study was to summarize the available literature on the effectiveness
of ambulatory nurse-led case management for complex patients in general health care. …

OBJECTIVE: Research in general practice has grown considerably over the past decades,
but many projects face problems when recruiting patients. Lasagna's Law states that medical …

BACKGROUND: It is believed that timely recognition and diagnosis of dementia is a pre-condition
for improving care for both older adults with dementia and their informal caregivers. …

BACKGROUND: To facilitate the development of clinical guidelines and to direct future
irritable bowel syndrome (IBS) research, insight into the perceptions of patients and general …