Over 11 million Americans have both diabetes and hypertension—comorbid diseases that
strongly predispose people to both renal as well as cardiovascular (CV) injury. Hypertension …

Background The effect of different classes of antihypertensive drugs on incident diabetes
mellitus is controversial because traditional meta-analyses are hindered by heterogeneity …

ContextHypertensive patients are often given a calcium antagonist to reduce cardiovascular
disease risk, but the benefit compared with other drug classes is controversial.ObjectiveTo …

Background and Purpose—Acute myocardial infarction and sudden death display a circadian
rhythm, with a higher risk between 6 am and noon. Some reports suggest that stroke does …

Many antihypertensive medications and lifestyle changes are proven to reduce blood
pressure. Over the past few decades, numerous additional modalities have been evaluated in …

(AHA) scientific statement “Treatment of Hypertension in the Prevention and Management of
Ischemic Heart Disease: A Scientific Statement From the American Heart Association …

Hypertension is a mechanism-based toxic effect of drugs that inhibit the vascular endothelial
growth factor signaling pathway (VSP). Substantial evidence exists for managing …

Key Points and Practical Recommendations• Calcium channel blockers, which dilate
arteries by reducing calcium flux into cells, effectively lower blood pressure, especially in …

Background: More than a decade ago, we found that a suboptimal medication regimen was
the leading cause of resistant hypertension (RH) among patients referred to a tertiary care …

Blood pressure (BP) control rates around the world are suboptimal. Part 2 of the National
Health and Nutrition Educational Survey (NHANES) III indicates that only 27.4% of …