Purpose: Because of the dismal outcomes of conventional therapies for pancreatic carcinomas,
we postulated that hypoxia may exist within these tumors. Methods and Materials: Seven …

PURPOSE: To determine the feasibility and toxicity of delivering stereotactic radiosurgery to
patients with locally advanced pancreatic cancer. METHODS AND MATERIALS: Patients …

Only 10% to 20% of patients with pancreatic cancer are considered candidates for curative
resection at the time of diagnosis. We postulated that preoperative chemoradiation therapy …

Purpose : CPT-11 sensitizes tumor cells to radiation and in combination therapy with 5-fluorouracil
(5-FU) results in enhanced cytotoxicity to metastatic colorectal cancer. We report the …

Postmastectomy chest wall and nodal radiation therapy decreases local recurrence and
improves disease‐free and overall survival. Immediate transverse rectus abdominis …

Mehta VK, Hao W, Brooks-Worrell BM, Palmer JP. Low-dose interleukin 1 and tumor necrosis
factor individually stimulate insulin release but in combination cause suppression. Eur J …

Hypotheses Adjuvant chemoradiotherapy decreases the risk of local recurrence in patients
with adenocarcinoma of the ampulla of Vater and high-risk features. Adjuvant …

The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total
dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this …

BACKGROUND: A prospective study was undertaken to evaluate the response and toxicity
of neoadjuvant chemoradiotherapy for ultrasound-staged T3 or T4 rectal cancer. PATIENTS …

Epidermal growth factor receptor (EGFR) is often overexpressed in tumors and has been
associated with poor prognosis in some cancer types. The introduction of inhibitors of EGFR, …