This article reviews research evidence showing to what extent the chronic care model can
improve the management of chronic conditions (using diabetes as an example) and reduce …

… Bodenheimer noted only GDP per capita and demographic trends related to our aging
population. No explicit consideration was given to the US legal system, which is unique when …

… The article on rising costs of health care made excellent reading and Dr Thomas Bodenheimer,
needs to be congratulated for the thought proving comments. Another interesting thought …

We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …

Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic
glioma driving alterations and suboptimal disease classification. We defined the complete …

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …

We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …

Patients with chronic conditions make day-to-day decisions about—self-manage—their
illnesses. This reality introduces a new chronic disease paradigm: the patient-professional …