OBJECTIVES Many older adults with limited life expectancy and/or advanced dementia (LLE/AD)
are potentially overtreated for diabetes and may benefit from deintensification. Our aim …

Background Deprescribing has been shown to reduce potentially inappropriate or unnecessary
medications; however, whether these benefits translate into improved quality of life (QOL…

Objectives To examine the association between central nervous system (CNS) medication
dosage burden and risk of serious falls, including hip fractures, in individuals with a history of …

BACKGROUND/OBJECTIVES Geriatric guidelines recommend against statin use in older
adults with limited life expectancy (LLE) or advanced dementia (AD). This study examined …

Background: Despite accumulating evidence about the harm of polypharmacy in family
medicine, few studies have investigated factors related to polypharmacy. The objective of this …

OBJECTIVE Guidelines advocate against tight glycemic control in older nursing home (NH)
residents with advanced dementia (AD) or limited life expectancy (LLE). We evaluated the …

Objectives Geriatric palliative care approaches support deprescribing of antihypertensives in
older nursing home (NH) residents with limited life expectancy and/or advanced dementia (…

Objectives To evaluate the predictive validity of an adapted version of the Minimum Data
Set (MDS) Mortality Risk Index—Revised (MMRI‐R) based on MDS version 3.0 assessment …

Introduction: Older adults often manage multiple medications simultaneously, contributing to
significant pill burden. Pill burden is a major concern for both patients and providers alike, …

In the last two decades in the United States (US), the previous research has focused on
medication optimization, including polypharmacy. Polypharmacy is associated with several …