User profiles for Sunil Thomas
 | Sunil ThomasLankenau Institute for Medical Research, Wynnewood, PA Verified email at mlhs.org Cited by 2457 |
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
GA Kolumam, S Thomas, LJ Thompson… - The Journal of …, 2005 - rupress.org
T cell expansion and memory formation are generally more effective when elicited by live
organisms than by inactivated vaccines. Elucidation of the underlying mechanisms is important …
organisms than by inactivated vaccines. Elucidation of the underlying mechanisms is important …
A benchmark study on problems related to CO2 storage in geologic formations: Summary and discussion of the results
This paper summarises the results of a benchmark study that compares a number of
mathematical and numerical models applied to specific problems in the context of carbon dioxide (…
mathematical and numerical models applied to specific problems in the context of carbon dioxide (…
Indoleamine 2, 3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
GC Prendergast, C Smith, S Thomas… - Cancer immunology …, 2014 - Springer
Genetic and pharmacological studies of indoleamine 2,3-dioxygenase (IDO) have established
this tryptophan catabolic enzyme as a central driver of malignant development and …
this tryptophan catabolic enzyme as a central driver of malignant development and …
The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists
Humans consider themselves discrete autonomous organisms, but recent research is
rapidly strengthening the appreciation that associated microorganisms make essential …
rapidly strengthening the appreciation that associated microorganisms make essential …
T‐cell tolerance or function is determined by combinatorial costimulatory signals
R Nurieva, S Thomas, T Nguyen… - The EMBO …, 2006 - embopress.org
Activated in immune responses, T lymphocytes differentiate into effector cells with potent
immune function. CD28 is the most prominent costimulatory receptor for T‐cell activation. …
immune function. CD28 is the most prominent costimulatory receptor for T‐cell activation. …
[HTML][HTML] The structure of the membrane protein of SARS-CoV-2 resembles the sugar transporter SemiSWEET
S Thomas - Pathogens and Immunity, 2020 - ncbi.nlm.nih.gov
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible
for the disease COVID-19 that has decimated the health and economy of our planet. The …
for the disease COVID-19 that has decimated the health and economy of our planet. The …
[HTML][HTML] IPS-1 is essential for the control of West Nile virus infection and immunity
The innate immune response is essential for controlling West Nile virus (WNV) infection but
how this response is propagated and regulates adaptive immunity in vivo are not defined. …
how this response is propagated and regulates adaptive immunity in vivo are not defined. …
Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation
LJ Thompson, GA Kolumam, S Thomas… - The Journal of …, 2006 - journals.aai.org
Type-I IFNs (IFN-I) provide direct survival signals to T cells during Ag-driven proliferation.
Because IFN-I production differs depending on the pathogen, we assessed CD8 T cell …
Because IFN-I production differs depending on the pathogen, we assessed CD8 T cell …
What really makes a promotional campaign succeed on a crowdfunding platform?: Guilt, utilitarian products, emotional messaging, and fewer but meaningful rewards …
Online crowdfunding is a popular platform for entrepreneurs to engage consumers by raising
funds for creative projects. The purpose of this research was to conceptualize a theoretical …
funds for creative projects. The purpose of this research was to conceptualize a theoretical …
Cancer vaccines: a brief overview
S Thomas, GC Prendergast - … Design: Methods and Protocols: Volume 1 …, 2016 - Springer
Vaccine approaches for cancer differ from traditional vaccine approaches for infectious
disease in tending to focus on clearing active disease rather than preventing disease. In this …
disease in tending to focus on clearing active disease rather than preventing disease. In this …