In the 117th Shattuck Lecture, Dr. Steven Schroeder asks why the American system fails to
deliver a standard of health similar to that observed in many other countries. In his arguments, …

Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …

The decrease in sequencing cost and increased sophistication of assembly algorithms for
short-read platforms has resulted in a sharp increase in the number of species with genome …

The Institute of Medicine of the National Academy of Sciences has just released a report on
quality assurance for the Medicare program. The legislation authorizing the study called for …

In 1995, a series of highly publicized medical incidents with serious adverse patient consequences
awakened public and professional interest in safety in health care. In response to this …

The health of the American public has never been better. Health reform, to date, has focused
primarily on health insurance. Although finding a way to expand health insurance coverage …

Tobacco use exerts a huge toll on persons with mental illnesses and substance abuse
disorders, accounting for 200,000 of the annual 443,000 annual tobacco-related deaths in the …

Despite the reality that smoking remains the most important preventable cause of death and
disability, most clinicians underperform in helping smokers quit. Of the 46 million current …

Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Background: Tobacco dependence treatment efforts have focused on primary care physicians
(PCPs), but evidence suggests that they are insufficient to help most smokers quit. Other …