Objectives : We sought to determine whether circulating soluble angiotensin-converting
enzyme 2 (sACE2) is increased in the plasma of patients with heart failure (HF). Background : …

Background Previous studies have independently validated the prognostic relevance of
residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from several …

Importance Pathologic complete response (pCR) is a known prognostic biomarker for long-term
outcomes. The I-SPY2 trial evaluated if the strength of this clinical association persists in …

We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …

Altered energy metabolism is a cancer hallmark as malignant cells tailor their metabolic
pathways to meet their energy requirements. Glucose and glutamine are the major nutrients that …

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies. The
aggressive behavior of ATC and its resistance to traditional treatment limit the efficacy of …

Protein kinases are frequently mutated in human cancer and inhibitors of mutant protein
kinases have proven to be effective anticancer drugs. We screened the coding sequences of …

Objective To examine whether perceived discrimination based on multiple personal
characteristics is associated with physical, emotional, and cognitive health concurrently, …

Subjective age, or how young or old individuals experience themselves to be relative to
their chronological age, is a crucial construct in gerontology. Subjective age is a significant …

We investigated the association between five factor model personality traits (neuroticism,
extraversion, openness, agreeableness, and conscientiousness) and risk of dementia, …