Background Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity
and mortality worldwide, and accurate estimates of the prevalence of this disease are …

Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …

Context Back and neck problems are among the symptoms most commonly encountered in
clinical practice. However, few studies have examined national trends in expenditures for …

Background: Increases in prescriptions of opioid medications for chronic pain have been
accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty about …

Background Budget impact analyses (BIAs) are an essential part of a comprehensive
economic assessment of a health care intervention and are increasingly required by …

COPD is one of the leading causes of morbidity and mortality worldwide and imparts a
substantial economic burden on individuals and society. Despite the intense interest in COPD …

Objectives: There is growing recognition that a comprehensive economic assessment of a
new health‐care intervention at the time of launch requires both a cost‐effectiveness analysis (…

The burden of hepatitis B virus (HBV) disease and efforts to control infection will determine
the future size of the population requiring treatment of HBV infection. To quantify the current …

ContextCentral venous catheters impregnated with chlorhexidine and silver sulfadiazine have
recently been introduced for the prevention of catheter-related infections. However, there …

Clinical trials evaluating medicines, medical devices, and procedures now commonly assess
the economic value of these interventions. The growing number of prospective clinical/…