Introduction: Primary care providers (PCPs) account for half of opioid prescriptions, often
feel chronic pain patients are challenging to manage, and there is wide variability in practice …

The mechanisms by which functional left/right asymmetry arises in morphologically symmetric
nervous systems are poorly understood. Here, we provide a mechanistic framework for …

MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

Background.—Training pediatric residents to care for the underserved is a recognized
curricular need. A literature review revealed that curricula specific to caring for the underserved …

… The lsy-6 expression pattern is reproduced with permission, from Cochella and Hobert,
2012a. The mir-791 expression pattern is reproduced from Drexel et al., 2016. (B) miRNA …

… The similarity of the effects suggests that these small molecules function independently of
specific interactions with the nucleotide variants per se. Rather, they overcome general …

Left/right asymmetric features of animals are either randomly distributed on either the left or
right side within a population (“antisymmetries”) or found stereotypically on one particular …

MicroRNAs (miRNAs) play an essential role in the post-transcriptional regulation of animal
development and physiology. However, in vivo studies aimed at linking miRNA function to the …

Combinatorial action of transcription factors (TFs) with partially overlapping expression is a
widespread strategy to generate novel gene-expression patterns and, thus, cellular diversity. …

The transcription factor Pax5 controls B cell development, but its role in mature B cells is
largely enigmatic. Here, we demonstrated that the loss of Pax5 by conditional mutagenesis in …