Human immunodeficiency virus-1 (HIV-1) infection is associated with numerous effects on
the nervous system, including pain and peripheral neuropathies. We now demonstrate that …

Background Ketamine infusions have been used for decades to treat acute pain, but a recent
surge in usage has made the infusions a mainstay of treatment in emergency departments, …

Background and Objectives: Gabapentin is an anticonvulsant that has been shown to be
effective in the treatment of neuropathic and inflammatory pain in animal and human studies. …

Background Sacroiliac joint pain is a challenging condition accounting for approximately 20%
of cases of chronic low back pain. Currently, there are no effective long-term treatment …

Background: The management of acute and chronic pain for individuals living with sickle cell
disease (SCD) is a clinical challenge. This reflects the paucity of clinical SCD pain research …

Background Over the past 2 decades, the use of intravenous ketamine infusions as a
treatment for chronic pain has increased dramatically, with wide variation in patient selection, …

Traditionally, biomedical research in the field of pain has been conducted with male animals
and subjects. Over the past 20–30 yr, it has been increasingly recognized that this narrow …

Obesity is associated with an increasing prevalence of musculoskeletal complaints and pain.
Obesity is a major risk factor for osteoarthritis (OA), and pain can manifest in load-bearing …

Background The past two decades have witnessed a surge in the use of lumbar facet blocks
and radiofrequency ablation (RFA) to treat low back pain (LBP), yet nearly all aspects of the …

Background Gabapentin and pregabalin are anticonvulsants with antihyperalgesic effects in
animal models of neuropathic and inflammatory nociception. This study characterized the …