… R. Allen reports no disclosures relevant to the manuscript. J. Campbell has consultancy or
research grants with Amgen, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Mallinckrodt…

Importance Histamine-2 receptor antagonists (H 2 RAs) and proton pump inhibitors (PPIs)
are commonly used to prevent gastrointestinal tract (GI) hemorrhage in critically ill patients. …

Context: The US FDA has issued an advisory warning of a possible link between
antidepressant treatment for paediatric patients with major depressive disorder (MDD) and an …

Introduction: Patients at risk for suicide often come into contact with primary care providers,
many of whom use electronic health records (EHRs) for charting. It is not known, however, …

Background: Although hypertension is a major risk factor for cardiovascular disease,
adherence to hypertensive medications is low. Previous research identifying factors influencing …

Rationale: Studies evaluating corticosteroid (CS) dosing for patients hospitalized with an acute
exacerbation of chronic obstructive pulmonary disease (AECOPD) have largely excluded …

Objectives: Recent evidence suggests that half-dose thrombolysis for pulmonary embolism
may provide similar efficacy with reduced bleeding risk compared with full-dose therapy, but …

Objective: Increased risk of diabetes and dyslipidemia is associated with major mental
illness and antipsychotic drug use. This study aimed to determine the prevalence of serum …

Data describing the use of recommended antihypertensive agents in the resistant hypertension
population are limited. Treatment recommendations for resistant hypertension include …

Rationale: The neuromuscular blocking agent cisatracurium may improve mortality for
patients with moderate-to-severe acute respiratory distress syndrome (ARDS). Other …