Background and Objectives: The goal of this study was to decrease admission and
readmission rate for the 2296 Medicaid patients in our clinic. Our focus was to eliminate patient …

Interferons (IFNs) are essential for host defense. Although the antiviral effects of the type 1
IFNs IFN-α and IFN-β (IFN-α/β) have been established, their immunoregulatory functions, …

Background Prior to DIEP flap breast reconstruction, mapping the perforators of the lower
abdominal wall using ultrasound, computed tomography angiography (CTA) or magnetic …

Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype
that we have previously shown 1 to be highly efficient for discovery of genetic associations 2 . …

The serine/threonine kinase tumor progression locus 2 (Tpl2, also known as Map3k8/Cot) is
a potent inflammatory mediator that drives the production of TNFα, IL-1β, and IFNγ. We …

In autoimmune diseases, the accumulation of activated leukocytes correlates with inflammation
and disease progression, and, therefore, the disruption of leukocyte trafficking is an …

Objective There are many uncertainties surrounding the aetiology, treatment and sequelae
of hyperemesis gravidarum (HG). Prioritising research questions could reduce research …

How does the law of judicial precedent work in practice? That is the question at the heart of
The Law of Judicial Precedent, the first treatise on the subject in more than ioo years. The …

Mitogen-activated protein kinase (MAP) cascades are important in antiviral immunity through
their regulation of interferon (IFN) production as well as virus replication. Although the …

Autoimmune diseases are approaching epidemic levels, estimated to affect 5–8% of the
population. A number of autoimmune diseases are believed to be driven by autoreactive T cells, …