Steroids are drugs that have been used extensively in a variety of conditions. Although widely
prescribed for their anti-inflammatory and immunosuppressive properties, glucocorticoids …

Objective To evaluate sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like
peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at varying …

Background— We sought to determine the concordance between the accumulating evidence
about the impact of tight versus less tight glycemic control in patients with type 2 diabetes …

Background Eliciting patient concerns and listening carefully to them contributes to patient-centered
care. Yet, clinicians often fail to elicit the patient’s agenda and, when they do, they …

Background Transgender individuals receive cross-sex hormonal therapy to induce desired
secondary sexual characteristics despite limited data regarding its effects on cardiovascular …

Background Adequate maternal thyroid function is important for an uncomplicated pregnancy.
Although multiple observational studies have evaluated the association between thyroid …

Objective To estimate the effectiveness and safety of thyroid hormone treatment among
pregnant women with subclinical hypothyroidism. Design Retrospective cohort study. Setting …

Purpose of Review Hypoglycemia is the most common and often treatment-limiting serious
adverse effect of diabetes therapy. Despite being potentially preventable, hypoglycemia in …

Clinical question What are the benefits and harms of sodium-glucose cotransporter 2 (SGLT-2)
inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists when added to usual …

Background Toluene is one of the most widely abused inhaled drugs due to its acute neurologic
effects including euphoria and subsequent depression. However, dangerous metabolic …