Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors

M Levis, P Brown, BD Smith, A Stine, R Pham, R Stone… - Blood, 2006 - ashpublications.org
We have developed a useful surrogate assay for monitoring the efficacy of FLT3 inhibition in
patients treated with oral FLT3 inhibitors. The plasma inhibitory activity (PIA) for FLT3 …

In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects

M Levis, R Pham, BD Smith, D Small - Blood, 2004 - ashpublications.org
… and linearity coefficient r. For all data reported here, r values were more than 0.95. The CI
is calculated using the formula: CI = (D) 1 /(Dm) 1 + (D) 2 /(Dm) 2 + (D) 1 (D) 2 /(Dm) 1 (Dm) 2 . …

Fast MRI breast cancer screening–Ready for prime time

S Partovi, D Sin, Z Lu, L Sieck, H Marshall, R Pham… - Clinical Imaging, 2020 - Elsevier
Objective The manuscript discusses landmark studies using abbreviated MRI for breast
cancer screening. This includes abbreviated dynamic contrast enhanced MRI and diffusion …

Definition and diagnosis of cerebral palsy in genetic studies: a systematic review

R Pham, BW Mol, J Gecz… - … Medicine & Child …, 2020 - Wiley Online Library
Aim To conduct a systematic review of phenotypic definition and case ascertainment in
published genetic studies of cerebral palsy (CP) to inform guidelines for the reporting of such …

Creating a shared understanding of testing culture on a social coding site

R Pham, L Singer, O Liskin… - 2013 35th …, 2013 - ieeexplore.ieee.org
… Randomly chosen interviewees from the first interview round are denoted with R, Coderwall
… Kinnaird, and R. Kang, “Social transparency in networked information exchange: a …

Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

M Levis, KM Murphy, R Pham, KT Kim, A Stine, L Li… - Blood, 2005 - ashpublications.org
Internal tandem duplication mutations of the FLT3 gene (FLT3/ITD mutations) are the most
frequent molecular abnormality in acute myeloid leukemia (AML) and are associated with a …

[HTML][HTML] Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma

JM Stiles, C Amaya, S Rains, D Diaz, R Pham… - PloS one, 2013 - journals.plos.org
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable
efficacy in the treatment of benign vascular tumors such as infantile hemangiomas. As infantile …

Geographic and population-level disparities in colorectal cancer testing: a multilevel analysis of Medicaid and commercial claims data

MM Davis, S Renfro, R Pham, KH Lich, J Shannon… - Preventive …, 2017 - Elsevier
Morbidity and mortality from colorectal cancer (CRC) can be attenuated through guideline
concordant screening and intervention. This study used Medicaid and commercial claims data …

[HTML][HTML] Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis

J Stiles, C Amaya, R Pham… - Experimental and …, 2012 - spandidos-publications.com
Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting
approximately 5-10% of children to varying degrees. During the first year of life, these …

DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators

…, D Kerrigan, J Markovits, R Pham - Nucleic Acids …, 1987 - academic.oup.com
… 2 N r * where r is the number of intercalated drug molecules per nucleotide and $ the DNA
unwinding angle for each intercalated molecule. Topoisomerase I action adjusts DNA linking …