Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors
We have developed a useful surrogate assay for monitoring the efficacy of FLT3 inhibition in
patients treated with oral FLT3 inhibitors. The plasma inhibitory activity (PIA) for FLT3 …
patients treated with oral FLT3 inhibitors. The plasma inhibitory activity (PIA) for FLT3 …
In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects
… and linearity coefficient r. For all data reported here, r values were more than 0.95. The CI
is calculated using the formula: CI = (D) 1 /(Dm) 1 + (D) 2 /(Dm) 2 + (D) 1 (D) 2 /(Dm) 1 (Dm) 2 . …
is calculated using the formula: CI = (D) 1 /(Dm) 1 + (D) 2 /(Dm) 2 + (D) 1 (D) 2 /(Dm) 1 (Dm) 2 . …
Fast MRI breast cancer screening–Ready for prime time
S Partovi, D Sin, Z Lu, L Sieck, H Marshall, R Pham… - Clinical Imaging, 2020 - Elsevier
Objective The manuscript discusses landmark studies using abbreviated MRI for breast
cancer screening. This includes abbreviated dynamic contrast enhanced MRI and diffusion …
cancer screening. This includes abbreviated dynamic contrast enhanced MRI and diffusion …
Definition and diagnosis of cerebral palsy in genetic studies: a systematic review
Aim To conduct a systematic review of phenotypic definition and case ascertainment in
published genetic studies of cerebral palsy (CP) to inform guidelines for the reporting of such …
published genetic studies of cerebral palsy (CP) to inform guidelines for the reporting of such …
Creating a shared understanding of testing culture on a social coding site
R Pham, L Singer, O Liskin… - 2013 35th …, 2013 - ieeexplore.ieee.org
… Randomly chosen interviewees from the first interview round are denoted with R, Coderwall
… Kinnaird, and R. Kang, “Social transparency in networked information exchange: a …
… Kinnaird, and R. Kang, “Social transparency in networked information exchange: a …
Internal tandem duplications of the FLT3 gene are present in leukemia stem cells
Internal tandem duplication mutations of the FLT3 gene (FLT3/ITD mutations) are the most
frequent molecular abnormality in acute myeloid leukemia (AML) and are associated with a …
frequent molecular abnormality in acute myeloid leukemia (AML) and are associated with a …
[HTML][HTML] Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma
JM Stiles, C Amaya, S Rains, D Diaz, R Pham… - PloS one, 2013 - journals.plos.org
Therapeutic targeting of the beta-adrenergic receptors has recently shown remarkable
efficacy in the treatment of benign vascular tumors such as infantile hemangiomas. As infantile …
efficacy in the treatment of benign vascular tumors such as infantile hemangiomas. As infantile …
Geographic and population-level disparities in colorectal cancer testing: a multilevel analysis of Medicaid and commercial claims data
Morbidity and mortality from colorectal cancer (CRC) can be attenuated through guideline
concordant screening and intervention. This study used Medicaid and commercial claims data …
concordant screening and intervention. This study used Medicaid and commercial claims data …
[HTML][HTML] Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis
J Stiles, C Amaya, R Pham… - Experimental and …, 2012 - spandidos-publications.com
Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting
approximately 5-10% of children to varying degrees. During the first year of life, these …
approximately 5-10% of children to varying degrees. During the first year of life, these …
DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators
…, D Kerrigan, J Markovits, R Pham - Nucleic Acids …, 1987 - academic.oup.com
… 2 N r * where r is the number of intercalated drug molecules per nucleotide and $ the DNA
unwinding angle for each intercalated molecule. Topoisomerase I action adjusts DNA linking …
unwinding angle for each intercalated molecule. Topoisomerase I action adjusts DNA linking …