The ends of human chromosomes are constituted of telomeres, a nucleoprotein complex.
They are mainly formed by the entanglement of repeat DNA and telomeric and non-telomeric …

Ligation‐mediated PCR was employed to quantify cyclobutane pyrimidine dimer (CPD)
formation at nucleotide resolution along exon 2 of the adenine phosphoribosyltransferase (aprt) …

The biological concept of microchimerism, the bidirectional trafficking and stable long-term
persistence of small numbers of allogeneic (fetal and maternal) cells in a genetically different …

Different types of nucleated fetal cells (trophoblasts, erythroblasts, lymphocytes, and
granulocytes) have been recovered in maternal peripheral blood. In spite of many attempts to …

P53 is a master transcriptional regulator controlling several main cellular pathways. Its role
is to adapt gene expression programs in order to maintain cellular homeostasis and genome …

Renal coloboma syndrome, also known as papillorenal syndrome is an autosomal‐dominant
disorder characterized by ocular and renal malformations. Mutations in the paired‐box …

Adaptor protein (AP) complexes regulate clathrin-coated vesicle assembly, protein cargo
sorting, and vesicular trafficking between organelles in eukaryotic cells. Because disruption of …

Ultraviolet light has been identified as the major carcinogen in skin cancer and the p53 tumor
suppressor gene is a major target for UV‐induced mutations. The mutations are probably …

The pathogenesis of endometriosis, a disease widely believed to arise from an aberrant
growth of endometrial tissue outside the uterus, is still unclear. We have previously observed …

DNA adducts in unique sequences along the mammalian genome are mapped in vivo at
single-nucleotide resolution. Pyrimidine (6-4) pyrimidone photoproducts [(6-4) photoproducts] …