User profiles for Paul R. Gordon

Paul R Gordon

University of Arizona
Verified email at email.arizona.edu
Cited by 2234

A next-generation TRK kinase inhibitor overcomes acquired resistance to prior TRK kinase inhibition in patients with TRK fusion–positive solid tumors

…, FX Sullivan, WE DeWolf, LA Wollenberg, PR Gordon… - Cancer discovery, 2017 - AACR
Larotrectinib, a selective TRK tyrosine kinase inhibitor (TKI), has demonstrated histology-agnostic
efficacy in patients with TRK fusion–positive cancers. Although responses to TRK …

Biology and Plasticity of CD133+ Hematopoietic Stem Cells

R Handgretinger, PR Gordon, T Leimig… - Annals of the new …, 2003 - Wiley Online Library
AC133 (CD133) is a highly conserved antigen expressed on hematopoietic stem cells with
unknown function. In order to further characterize CD133 + progenitor cells, we purified …

Chemical stabilisation of collagen as a biomimetic

RG Paul, AJ Bailey - The Scientific World Journal, 2003 - hindawi.com
Collagen is the most abundant protein in animals and because of its high mechanical
strength and good resistance to degradation has been utilized in a wide range of products in …

The effect of advanced glycation end-product formation upon cell-matrix interactions

RG Paul, AJ Bailey - The international journal of biochemistry & cell biology, 1999 - Elsevier
The formation of advanced glycation end-products plays a central role in the progressive
deterioration of tissues with age, a process that is accelerated in diabetes. Collagen in addition …

Sertraline to treat hot flashes: a randomized controlled, double-blind, crossover trial in a general population

PR Gordon, JP Kerwin, KG Boesen, J Senf - Menopause, 2006 - journals.lww.com
Objective: To evaluate the effectiveness of a selective serotonin reuptake inhibitor (SSRI)(sertraline)
in decreasing hot flashes in a general population of women. Design: A double-blind, …

[HTML][HTML] Effect of an integrated nutrition curriculum on medical education, student clinical performance, and student perception of medical-nutrition training

DL Taren, CA Thomson, NA Koff, PR Gordon… - The American journal of …, 2001 - Elsevier
Background: Ninety-eight percent of medical schools report nutrition as a component of
medical education. However, most schools do not have an identifiable nutrition curriculum. …

[HTML][HTML] Reactions of lipid-derived malondialdehyde with collagen

DA Slatter, RG Paul, M Murray, AJ Bailey - Journal of Biological Chemistry, 1999 - ASBMB
Malondialdehyde is a product of fatty acid oxidation (eg from low density lipoprotein) implicated
in the damage of proteins such as collagen in the cardiovascular system (Chio, KJ, and …

KnowPain-50: a tool for assessing physician pain management education

JM Harris Jr, JV Fulginiti, PR Gordon, TE Elliott… - Pain …, 2008 - academic.oup.com
Background. Despite a need for better physician pain management education, there are no
widely accepted assessment or outcome measures to support this work. Objective. Create a …

Isolation and characterization of advanced glycation end products derived from the in vitro reaction of ribose and collagen

RG PAUL, CN AVERY, AD SLATTER… - Biochemical …, 1998 - portlandpress.com
An amino acid component, NFC-1, when formed in vitro by the reaction of ribose and protein
was shown to comprise a complex mixture of high and low molecular AGE compounds. Two …

The variable response of women with menopausal hot flashes when treated with sertraline

JP Kerwin, PR Gordon, JH Senf - Menopause, 2007 - journals.lww.com
Objective: To evaluate the variable response of women when treated with a selective serotonin
reuptake inhibitor (sertraline) to decrease hot flashes. Design: A double-blind, placebo-…