Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

S Einav, D Gerber, PD Bryson, EH Sklan… - Nature …, 2008 - nature.com
More effective therapies are urgently needed against hepatitis C virus (HCV), a major cause
of viral hepatitis. We used in vitro protein expression and microfluidic affinity analysis to …

Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results

CA Rosen, PC Bryson - Journal of Voice, 2004 - Elsevier
We report the results of a clinical study using Indole-3-Carbinol (I3C) for the treatment of
recurrent respiratory papillomatosis (RRP). I3C is abundant in cruciferous vegetables and has …

Disease homogeneity and treatment heterogeneity in idiopathic subglottic stenosis

…, G Sandhu, MS Benninger, PC Bryson… - The …, 2016 - Wiley Online Library
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is a rare and potentially life‐threatening
disease marked by recurrent and progressive airway obstruction frequently requiring …

Comparative treatment outcomes for patients with idiopathic subglottic stenosis

…, JH Blumin, JM Bock, PC Bryson… - … –Head & Neck …, 2020 - jamanetwork.com
Importance Surgical treatment comparisons in rare diseases are difficult secondary to the
geographic distribution of patients. Fortunately, emerging technologies offer promise to reduce …

[HTML][HTML] Masked chimeric antigen receptor for tumor-specific activation

X Han, PD Bryson, Y Zhao, GE Cinay, S Li, Y Guo… - Molecular Therapy, 2017 - cell.com
Adoptive cellular therapy based on chimeric antigen receptor (CAR)-engineered T (CAR-T)
cells is a powerful form of cancer immunotherapy. CAR-T cells can be redirected to …

[HTML][HTML] Combination cancer therapy using chimeric antigen receptor-engineered natural killer cells as drug carriers

…, X Chen, N Siriwon, J Mac, JA Rohrs, PD Bryson… - Molecular Therapy, 2017 - cell.com
The therapeutic limitations of conventional chemotherapeutic drugs include chemo-resistance,
tumor recurrence, and metastasis. Numerous nanoparticle-based active targeting …

A multimodal multi-institutional solution to remote medical student education for otolaryngology during COVID-19

…, A Kominsky, TD Otteson, PC Bryson… - … –Head and Neck …, 2020 - journals.sagepub.com
During the coronavirus 2019 pandemic, there has been a surge in production of remote
learning materials for continued otolaryngology resident education. Medical students …

[HTML][HTML] In vivo expansion and antitumor activity of coinfused CD28-and 4-1BB-engineered CAR-T cells in patients with B cell leukemia

…, B Wei, J Chen, H Fang, X Han, JA Rohrs, P Bryson… - Molecular Therapy, 2018 - cell.com
Several recent clinical trials have successfully incorporated a costimulatory domain derived
from either CD28 or 4-1BB with the original CD3ζ T cell activating domain to form second-…

Prevalence and occupation of patients presenting with dysphonia in the United States

MS Benninger, CE Holy, PC Bryson, CF Milstein - Journal of Voice, 2017 - Elsevier
Objective Voice disorders are common conditions that may have a significant impact on patient
quality of life, yet their prevalence and epidemiology are poorly documented. In this study…

Utility of transnasal humidified rapid insufflation ventilatory exchange for microlaryngeal surgery

…, WS Tierney, B Abdelmalak, PC Bryson - The …, 2021 - Wiley Online Library
Objective Microlaryngeal surgery typically requires oxygenation and ventilation via either an
endotracheal tube (ETT), jet ventilation (JV), or intermittent apnea with an ETT. Transnasal …