The proprotein convertases (PCs) are a seven‐member family of endoproteases that activate
proproteins by cleavage at basic motifs. Expression patterns for individual PCs vary widely, …

The amyloid peptide is the main constituent of the amyloid plaques in brain of Alzheimer's
disease patients. This peptide is generated from the amyloid precursor protein by two …

… For immunoprecipitations an anti-ADAM17 chicken IgY polyclonal antibody raised against
recombinant ADAM17 was used (NA Taylor, unpublished work). siRNA (small interfering RNA…

The hyt/hyt hypothyroid mouse has an autosomal recessive, fetal-onset, severe hypothyroidism
related to TSH hyporesponsiveness and associated with elevated TSH. Our previous …

The question in my title," whose art are we studying?," comes from Stanley O'Connor. In
asking it, he wanted his students to be reminded that art is" there" because someone made it, …

The biosynthesis and secretion of human proinsulin and a mutant human proinsulin with a
major deletion in the C-peptide, (des 38–62)proinsulin, was studied in monkey kidney cells (…

In this study we examined anteroposterior cephalometric changes in children enrolled in a
randomized controlled trial of early treatment for Class II malocclusion. Children, aged 9.6 ± …

… In the course of studies on the role of cytosolic calcium in the action of vasopressin, Taylor
(… In the toad bladder (48; and Taylor, unpublished results), addition of quinidine to the serosal …

Background Population-based estimates of the risk of breast cancer associated with
germline pathogenic variants in cancer-predisposition genes are critically needed for risk …

Sporadic Parkinson's disease (PD) is most likely caused by a combination of environmental
exposures and genetic susceptibilities, although there are rare monogenic forms of the …