[HTML][HTML] The CD8 T cell response to respiratory virus infections
ME Schmidt, SM Varga - Frontiers in immunology, 2018 - frontiersin.org
Humans are highly susceptible to infection with respiratory viruses including respiratory
syncytial virus (RSV), influenza virus, human metapneumovirus, rhinovirus, coronavirus, and …
syncytial virus (RSV), influenza virus, human metapneumovirus, rhinovirus, coronavirus, and …
[HTML][HTML] Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection
ME Schmidt, CJ Knudson, SM Hartwig, LL Pewe… - PLoS …, 2018 - journals.plos.org
Memory CD8 T cells can provide protection from re-infection by respiratory viruses such as
influenza and SARS. However, the relative contribution of memory CD8 T cells in providing …
influenza and SARS. However, the relative contribution of memory CD8 T cells in providing …
[HTML][HTML] Tissue-resident memory T cells in the lungs protect against acute respiratory syncytial virus infection
MA Luangrath, ME Schmidt, SM Hartwig… - …, 2021 - journals.aai.org
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in
young children. The T cell response plays a critical role in facilitating clearance of an acute …
young children. The T cell response plays a critical role in facilitating clearance of an acute …
Cytokines and CD8 T cell immunity during respiratory syncytial virus infection
ME Schmidt, SM Varga - Cytokine, 2020 - Elsevier
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection and
hospitalization in infants. In spite of the enormous clinical burden caused by RSV infections, …
hospitalization in infants. In spite of the enormous clinical burden caused by RSV infections, …
Modulation of the host immune response by respiratory syncytial virus proteins
ME Schmidt, SM Varga - Journal of Microbiology, 2017 - Springer
Respiratory syncytial virus (RSV) causes severe respiratory disease in both the very young
and the elderly. Nearly all individuals become infected in early childhood, and reinfections …
and the elderly. Nearly all individuals become infected in early childhood, and reinfections …
Microparticle delivery of a STING agonist enables indirect activation of NK cells by antigen-presenting cells
…, CJ Batty, RT Stiepel, ME Schmidt… - Molecular …, 2022 - ACS Publications
Natural killer (NK) cells are an important member of the innate immune system and can
participate in direct tumor cell killing in response to immunotherapies. One class of …
participate in direct tumor cell killing in response to immunotherapies. One class of …
[HTML][HTML] Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection
ME Schmidt, DK Meyerholz, SM Varga - Mucosal immunology, 2020 - nature.com
Despite being a leading cause of severe respiratory disease, there remains no licensed
respiratory syncytial virus (RSV) vaccine. Neutralizing antibodies reduce the severity of RSV-…
respiratory syncytial virus (RSV) vaccine. Neutralizing antibodies reduce the severity of RSV-…
[HTML][HTML] A live single-cycle RSV vaccine expressing prefusion F protein
P Lamichhane, ME Schmidt, M Terhüja, SM Varga… - Virology, 2022 - Elsevier
Live-attenuated Respiratory syncytial virus (RSV) vaccines given intranasally have potential
to provide comprehensive protection, including lung-resident immunity. It has however …
to provide comprehensive protection, including lung-resident immunity. It has however …
Prognostic indices for advance care planning in primary care: a scoping review
…, MA Berry-Stoelzle, ME Schmidt… - The Journal of the …, 2020 - Am Board Family Med
Background: Patient identification is an important step for advance care planning (ACP)
discussions. Objectives: We conducted a scoping review to identify prognostic indices potentially …
discussions. Objectives: We conducted a scoping review to identify prognostic indices potentially …
Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection
…, LN Mallinger, T Arkee, ME Schmidt… - Journal of Leucocyte …, 2021 - academic.oup.com
Many acute viral infections target tissue Mϕs, yet the mechanisms of Mϕ-mediated control
of viruses are poorly understood. Here, we report that CD40 expressed by peritoneal Mϕs …
of viruses are poorly understood. Here, we report that CD40 expressed by peritoneal Mϕs …