Impaired wound healing results in significant morbidity for the surgical patient. The
genetically diabetic (C57BL/KsJ-db/db) mouse is obese, hyperglycemic, insulin-resistant, and …

The definition and classification of cardiomyopathy have evolved considerably in recent
years. Cardiomyopathy can be separated into primary (genetic, mixed, or acquired) and …

Topical application of growth factors has been shown to benefit both normal and impaired
wound healing. In normal tissue repair, resident cells produce a “cocktail” of various types of …

After observing several cases of endocarditis-related deaths, we determined the contribution
of cardiac abnormalities to burn mortality. Autopsy reports of all burn-related deaths …

Background: The literature on results from primary care–based opioid-prescribing protocols
is small and results have been mixed. To advance this field, we evaluated whether opioid …

No. Cryotherapy with liquid nitrogen may be superior in clearing genital warts when directly
compared to topical podophyllin treatments (SOR: C, small randomized controlled trial [RCT])…

In general, thromboprophylaxis does not appear to reduce venothromboembolism events in
patients with cirrhosis or increase the risk of bleeding (SOR: B, meta-analysis of cohort …

We have recently demonstrated induction of expression of several members of the fibroblast
growth factor family during wound healing, particularly for keratinocyte growth factor, which …

Objective: Many ADMs can alter blood pressure (BP), but the research on the effect of
antidepressant medication (ADMs) on incident hypertension is mixed. We investigated whether the …

Background Though inconsistent, the majority of studies support an association between
depression and incident hypertension and poor blood pressure control. However, none have …