… By using a between-session protocol of relapse, Spano and colleagues have demonstrated
how in these animals an acute intraperitoneal (ip) priming of the same CB-sub1 receptor …

There is currently substantial evidence that Cannabis sativa derivates act on brain reward in
a way very similar to other drugs of abuse and exert numerous pharmacological effects …

… induced nausea and vomiting, appetite stimulation in patients with AIDS as well as in the
relief from spasticity, neuropathic pain and sleep disturbances in patients with multiple sclerosis…

Background and purpose: We recently demonstrated the existence of strain differences in
self‐administration of the cannabinoid CB 1 receptor agonist WIN55,212‐2 (WIN) by Long …

BACKGROUND: Prenatal cannabis exposure is a growing concern with little known about
the long-term consequences on behavior and neural systems relevant for reward and …

Background and purpose: Animal and human studies have shown that sex and hormones
are key factors in modulating addiction. Previously, we have demonstrated that self‐…

In the present study, dopamine release was monitored during cannabinoid self-administration
in rats to achieve a detailed understanding of the way in which dopamine mediates the …

Because opioid and cannabinoid systems have been reported to interact in the modulation of
addictive behaviour, this study was aimed at investigating the ability of cannabinoid agents …

Cannabinoids have been reported to sustain self-administration in laboratory animals;
however, genetic differences and environmental factors critical in the initiation and retention of …

… The first and the third blocks consisted of 5 pulse-alone trials of 40 ms at 115 dB, while
the second block (test block) was a pseudorandom sequence of 50 trials including 12 pulse-…