Outpatient antibiotic stewardship: interventions and opportunities

…, ME Klepser, JM Pogue, MJ Labreche… - Journal of the American …, 2017 - Elsevier
Improving the use of antibiotics across the continuum of care is a national priority. Data
outlining the misuse of antibiotics in the outpatient setting justify the expansion of antibiotic …

[HTML][HTML] The environmental and social influences of HIV/AIDS in sub-Saharan Africa: a focus on rural communities

CU Oramasionwu, KR Daniels, MJ Labreche… - International journal of …, 2011 - mdpi.com
The Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS)
pandemic has caused far-reaching effects in sub-Saharan Africa. The pandemic has effectively …

Recent updates on the role of pharmacokinetics-pharmacodynamics in antimicrobial susceptibility testing as applied to clinical practice

MJ Labreche, CJ Graber… - Clinical Infectious …, 2015 - academic.oup.com
Given current challenges in antimicrobial resistance and drug development, infectious diseases
clinicians must rely on their own ingenuity to effectively treat infections while preserving …

Evaluation of the nanosphere Verigene BC-GN assay for direct identification of gram-negative bacilli and antibiotic resistance markers from positive blood cultures and …

…, KDT Tran, KL Barton, MJ Labreche… - Journal of clinical …, 2014 - Am Soc Microbiol
The Verigene BC-GN assay correctly identified all 51 Gram-negative bacilli (GNB) from
positive blood cultures and all 14 carbapenemase enzymes tested. The assay gave organism …

Treatment failure and costs in patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections: a South Texas Ambulatory Research …

MJ Labreche, GC Lee, RT Attridge… - The Journal of the …, 2013 - Am Board Family Med
Objective: To measure the incidence of treatment failure and associated costs in patients with
methicillin-resistant Staphylococcus aureus skin and soft tissue infections (SSTIs). Methods…

Evaluation of dexmedetomidine versus propofol-based sedation therapy in mechanically ventilated cardiac surgery patients at a tertiary academic medical center

…, PM Szumita, SA Baroletti, MJ Labreche… - Critical pathways in …, 2010 - journals.lww.com
Management of pain and sedation therapy is a vital component of optimizing patient
outcomes; however, the ideal pharmacotherapy regimen has not been identified in the …

A call to action for outpatient antibiotic stewardship

…, EL Dobson, JM Pogue, MJ Labreche… - Journal of the American …, 2017 - Elsevier
Objectives To address the public health threat of antibiotic resistance, there has been an
enhanced call for antibiotic stewardship programs throughout the health care continuum. …

[HTML][HTML] Fluoroquinolones in community-acquired pneumonia: guide to selection and appropriate use

CR Frei, MJ Labreche, RT Attridge - Drugs, 2011 - Springer
Fluoroquinolone use has dramatically increased since the introduction of the first respiratory
fluoroquinolone in the late 1990s. Over a relatively brief period of time, the respiratory …

[HTML][HTML] Comparative value of four measures of retention in expert care in predicting clinical outcomes and health care utilization in HIV patients

KR Reveles, TR Juday, MJ Labreche, EM Mortensen… - PloS one, 2015 - journals.plos.org
This study compared the ability of four measures of patient retention in HIV expert care to
predict clinical outcomes. This retrospective study examined Veterans Health Administration (…

Declining susceptibilities of gram-negative bacteria to the fluoroquinolones: effects on pharmacokinetics, pharmacodynamics, and clinical outcomes

MJ Labreche, CR Frei - American Journal of Health-System …, 2012 - academic.oup.com
Purpose Published evidence of rising gram-negative bacterial resistance to fluoroquinolone
therapy is reviewed, with a focus on the potential need for revising pharmacokinetic–…