Predictors of COVID‐19 severity: a literature review

…, TP Salazar‐Mather, L Dumenco… - Reviews in medical …, 2021 - Wiley Online Library
The coronavirus disease 2019 (COVID‐19) pandemic is a rapidly evolving global emergency
that continues to strain healthcare systems. Emerging research describes a plethora of …

The Prevention of Thymic Lymphomas in Transgenic Mice by Human O6-Alkylguanine-DNA Alkyltransferase

LL Dumenco, E Allay, K Norton, SL Gerson - Science, 1993 - science.org
Nitrosoureas form O 6 -alkylguanine-DNA adducts that are converted to G to A transitions,
the mutation found in the activated ras oncogenes of nitrosourea-induced mouse lymphomas …

An interprofessional education workshop to develop health professional student opioid misuse knowledge, attitudes, and skills

K Monteiro, L Dumenco, S Collins, J Bratberg… - Journal of the American …, 2017 - Elsevier
Objective To implement and evaluate an interprofessional workshop focused on increasing
student knowledge, skills, and attitudes toward opioid misuse. Setting The Warren Alpert …

Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon

…, TP Pretlow, MA O'Riordan, LL Dumenco… - …, 1995 - academic.oup.com
Transgenic mice over-expressing MGMT, which codes for the human protein O 6 -alkylguanine-DNA
alkyltransferase, are protected from methylating agent-induced thymic lymphomas. …

Incorporating iPads into a preclinical curriculum: A pilot study

P George, L Dumenco, R Doyle, R Dollase - Medical Teacher, 2013 - Taylor & Francis
Background: The incorporation of technology into medical education is critical for learners.
Little is known about the effect of integrating iPad technology into undergraduate medical …

Introducing technology into medical education: two pilot studies

P George, L Dumenco, R Dollase, JS Taylor… - Patient education and …, 2013 - Elsevier
Objectives Educators are integrating new technology into medical curriculum. The impact of
newer technology on educational outcomes remains unclear. We aimed to determine if two …

A qualitative analysis of interprofessional students' perceptions toward patients with opioid use disorder after a patient panel experience

L Dumenco, K Monteiro, S Collins… - Substance …, 2019 - journals.sagepub.com
Background: Students from health professional schools participated in a half-day interprofessional
education workshop centered on substance use disorder training. One component …

Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells

JA Allay, LL Dumenco, ON Koc, L Liu, SL Gerson - 1995 - ashpublications.org
Myelosuppression is the dose-limiting toxicity for nitrosourea chemotherapy. This toxicity
predominantly involves modification of the O6 position of guanine with an alkyl moiety. The …

Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU

SL Gerson, W Phillips, M Kastan, LL Dumenco… - 1996 - ashpublications.org
Human bone marrow (BM) cells contain low levels of the DNA repair protein, O6-alkylguanine-DNA
alkyltransferase, which may explain their susceptibility to nitrosourea-induced …

Opioid overdose hospitalizations among Medicare-disability beneficiaries

…, WM Durand, KA Monteiro, L Dumenco… - The Journal of the …, 2018 - Am Board Family Med
Introduction: As the opioid epidemic progresses, a better understanding of those at elevated
risk of opioid overdose is needed, particularly for populations whose growing risk may be …