Background In diagnostic studies, a single and error-free test that can be used as the
reference (gold) standard often does not exist. One solution is the use of panel diagnosis, ie, a …

Background: chronic dyspnoea is common in older people and is often of cardiac or pulmonary
aetiology. Information on the exact prevalence and distribution of underlying causes is …

Background Preterm birth is the leading cause of child mortality globally, with many survivors
experiencing long-term adverse consequences. Preliminary evidence suggests that …

Background The health of an (unborn) child is largely determined by the health and social
determinants of its parents. The extent to which social determinants of parents or prospective …

Combining several tests is a common way to improve the final classification of disease
status in diagnostic accuracy studies but is often used ambiguously. This article gives advice …

Objectives The purpose of our study was to investigate the association of different socioeconomic
and sociodemographic factors with dental caries in six-year-old children. Furthermore, …

Purpose Prediction models for exacerbations in patients with chronic obstructive pulmonary
disease (COPD) are scarce. Our aim was to develop and validate a new model to predict …

Background Geographical inequalities in perinatal health and child welfare require attention.
To improve the identification, and care, of mothers and young children at risk of adverse …

Background: Reduced exercise tolerance and dyspnea are common in older people, and
heart failure (HF) and chronic obstructive pulmonary disease (COPD) are the main causes. We …

Background Adverse birth outcomes have serious health consequences, not only during
infancy but throughout the entire life course. Most evidence linking neighbourhood …