Objective Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can
be regulated through mitochondrial transmembrane potential (Δψm) and mammalian target …

Background Patients with systemic lupus erythematosus have T-cell dysfunction that has
been attributed to the activation of the mammalian target of rapamycin (mTOR). Rapamycin …

The higher prevalence of cardiovascular disease in obese individuals is indirectly mediated,
to a large extent, by the increased frequency of various well known risk factors like …

The mechanistic target of rapamycin (mTOR) is recognized as a sensor of mitochondrial
dysfunction and effector of T cell lineage development; however, its role in autoimmunity, …

Objective To investigate whether attention deficit hyperactivity disorder (ADHD) may serve as
a marker of neuropsychiatric disease and as a target for N‐acetylcysteine (NAC) treatment …

Emergency physicians routinely provide sedation and analgesia, monitor the respiratory and
cardiovascular status, and manage critically ill patients of all ages. 1-3 The provision of safe …

Infectious agents have long been implicated in the pathogenesis of systemic lupus
erythematosus. Common viruses, such as the Epstein-Barr virus, transfusion transmitted virus, …

Liver disease (LD), defined as ≥ 2-fold elevation of aspartate aminotransferase (AST) or
alanine aminotransferase (ALT), was examined in a longitudinal study of systemic lupus …

Tumor necrosis factor-α (TNF-α) inhibitors are considered safe and effective for treatment of
rheumatoid arthritis (RA) and psoriatic arthritis (PsA) 1. Although induction of antinuclear …

Antinuclear antibodies (ANA) are a hallmark of systemic lupus erythematosus (SLE) and
one of its key diagnostic criteria. Recently, new technologies based on antibody binding to …