Background: Overdose deaths involving opioid pain relievers (OPR), also known as opioid
analgesics, have increased and now exceed deaths involving heroin and cocaine combined. …

ContextDaily consumption of 400 µg of folic acid before conception and during early
pregnancy dramatically reduces the occurrence of neural tube defects (NTDs). Before food …

Context Use and abuse of prescription narcotic analgesics have increased dramatically in
the United States since 1990. The effect of this pharmacoepidemic has been most …

Objective. Hypospadias is a common congenital anomaly, the cause of which is unknown.
Unexplained increases in the rates of hypospadias occurred in five European countries in the …

Purpose Since 1990, numerous jurisdictions in the United States (US) have reported increases
in drug poisoning mortality. During the same time period, the use of opioid analgesics …

This analysis confirms the predominant role opioid analgesics play in pharmaceutical overdose
deaths, either alone or in combination with other drugs. It also, however, highlights the …

Researchers from seven European nations and the United States have published reports of
increasing rates of hypospadias during the 1960s, 1970s, and 1980s. Reports of increasing …

Objective. Drug overdoses resulting from the abuse of prescription opioid analgesics and
other controlled substances have increased in number as the volume of such drugs prescribed …

Background: Overprescribing of opioid pain relievers (OPR) can result in multiple adverse
health outcomes, including fatal overdoses. Interstate variation in rates of prescribing OPR …

Problem: In 2005, 15,802 persons aged ≥65 years died from fall injuries. How many older
adults seek outpatient treatment for minor or moderate fall injuries is unknown. Method: To …