Despite the success of tyrosine kinase-based cancer therapeutics, for most solid tumors the
tyrosine kinases that drive disease remain unknown, limiting our ability to identify drug …

Aldehyde dehydrogenase (ALDH) is a candidate marker for lung cancer cells with stem cell-like
properties. Immunohistochemical staining of a large panel of primary non–small cell …

Artificial intelligence and brain–computer interfaces must respect and preserve people's
privacy, identity, agency and equality, say Rafael Yuste, Sara Goering and colleagues.

Purpose Angiogenesis is important for epithelial ovarian cancer (EOC) growth, and blocking
angiogenesis can lead to EOC regression. Cediranib is an oral tyrosine kinase inhibitor (TKI…

How inflammation causes cancer is unclear. Interleukin-15 (IL-15) is a pro-inflammatory
cytokine elevated in human large granular lymphocyte (LGL) leukemia. Mice overexpressing IL-…

Interleukin-15 (IL-15) is a proinflammatory cytokine involved in the development, survival,
proliferation, and activation of multiple lymphocyte lineages utilizing a variety of signaling …

Angiogenesis is required in normal physiological processes, but is also involved in tumor
growth, progression and metastasis. Vascular endothelial growth factor (VEGF), a primary …

Vascular endothelial growth factor (VEGF) is a primary stimulant of angiogenesis and is a
macrophage chemotactic protein. Inhibition of VEGF is beneficial in combination with …

As the United States rapidly becomes both a more diverse and unequal nation, policymakers
face the urgent challenge of confronting growing wealth gaps by race and ethnicity. To …

Increasingly, national governments across the globe are prioritizing investments in neuroscience.
Currently, seven active or in-development national-level brain research initiatives exist…