[HTML][HTML] Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes

A Heintz-Buschart, P May, CC Laczny, LA Lebrun… - Nature …, 2016 - nature.com
The gastrointestinal microbiome is a complex ecosystem with functions that shape human
health. Studying the relationship between taxonomic alterations and functional repercussions …

Effects of length of stay and language proficiency on health care experiences among immigrants in Canada and the United States

LA Lebrun - Social science & medicine, 2012 - Elsevier
This study sought to examine the influence of length of stay and language proficiency on
immigrants’ access to and utilization of care in Canada and the United States (US). Data came …

The influence of English proficiency on access to care

L Shi, LA Lebrun, J Tsai - Ethnicity & health, 2009 - Taylor & Francis
Objective. The number of individuals with limited English proficiency in the USA is large and
rapidly growing. Consequently, addressing language barriers in access to medical care is …

Health, behavior, and health care disparities: disentangling the effects of income and race in the United States

LC Dubay, LA Lebrun - International Journal of Health …, 2012 - journals.sagepub.com
The literature on health disparities in the United States typically focuses on race/ethnicity or
on socioeconomic status (SES) separately, but not often together. The purpose of the study …

Discovery of CRBN E3 ligase modulator CC-92480 for the treatment of relapsed and refractory multiple myeloma

…, D Mendy, F Baculi, LA LeBrun… - Journal of medicinal …, 2020 - ACS Publications
Many patients with multiple myeloma (MM) initially respond to treatment with modern combination
regimens including immunomodulatory agents (lenalidomide and pomalidomide) and …

CC-90009: a cereblon E3 ligase modulating drug that promotes selective degradation of GSPT1 for the treatment of acute myeloid leukemia

…, D Huang, J Sapienza, G Lu, LA LeBrun… - Journal of medicinal …, 2021 - ACS Publications
Acute myeloid leukemia (AML) is marked by significant unmet clinical need due to both poor
survival and high relapse rates where long-term disease control for most patients with …

Development of the Chinese primary care assessment tool: data quality and measurement properties

H Yang, L Shi, LA Lebrun, X Zhou, J Liu… - … journal for quality in …, 2013 - academic.oup.com
Objective The aim of this study was to translate and adapt the Primary Care Assessment
Tool to assess the perceptions of the quality of primary care among patients in China and to …

[HTML][HTML] Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance

…, AR Sheik, LAK Kleine-Borgmann, LA Lebrun… - Nature …, 2020 - nature.com
The development of reliable, mixed-culture biotechnological processes hinges on
understanding how microbial ecosystems respond to disturbances. Here we reveal extensive …

[HTML][HTML] Comparative integrated omics: identification of key functionalities in microbial community-wide metabolic networks

…, CC Laczny, S Narayanasamy, LA Lebrun… - npj Biofilms and …, 2015 - nature.com
Background: Mixed microbial communities underpin important biotechnological processes
such as biological wastewater treatment (BWWT). A detailed knowledge of community …

Access to primary and preventive care among foreign‐born adults in Canada and the United States

LA Lebrun, LC Dubay - Health Services Research, 2010 - Wiley Online Library
Objective. To conduct cross‐country comparisons and assess the effect of foreign birth on
access to primary and preventive care in Canada and the United States. Data Sources. …