User profiles for Juan C. Nogues

juan nogues

Verified email at gwu.edu
Cited by 7

Human papillomavirus-associated head and neck cancer

JC Nogues, S Fassas, C Mulcahy… - The Journal of the …, 2021 - Am Board Family Med
Oropharyngeal squamous cell carcinoma (OPSCC) has historically been attributable to
tobacco and alcohol exposure and saw a decline in incidence after societal norms shifted away …

Review of otitis media microbiome studies: What do they tell us?

JC Nogues, M Pérez‐Losada… - Laryngoscope …, 2020 - Wiley Online Library
Objectives To provide a state of the art review on accruing studies focused on defining the
middle ear microbiome, highlighting the relationship of the microbiome to disease …

Obstructive sleep apnea for the rhinologist

JC Nogues, N Jain, CT Chou… - Current Opinion in …, 2024 - journals.lww.com
Purpose Obstructive sleep apnea (OSA) is a ubiquitous disease defined by repetitive partial
or complete cessation of airflow during sleep caused by upper airway collapse. …

Optimizing protonation states for selective double-strand DNA photocleavage in hypoxic tumors: pH-gated transitions of lysine dipeptides

K Kaya, S Roy, JC Nogues, JC Rojas… - Journal of Medicinal …, 2016 - ACS Publications
We report pH-switching properties of the new family of dipeptide–acetylene conjugates where
pH-gated light-activated double-strand (ds) DNA cleavage is controlled by variations in …

Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq

…, JC Rivera-Mulia, C Trevilla-García, C Nogues… - Nature protocols, 2018 - nature.com
Cycling cells duplicate their DNA content during S phase, following a defined program called
replication timing (RT). Early-and late-replicating regions differ in terms of mutation rates, …

[HTML][HTML] The effect of TET mutations on DNA methyltransferase cytotoxicity and ERV induction in B and T cell malignancies

JC Nogues, ZM Wang, SS Chisholm, M Smith… - Blood, 2018 - Elsevier
Cancers exhibit altered DNA methylation compared to normal cells, including methylation
loss at regions normally silenced for genome stability and gain at promoter regions of tumor …

Incidentally discovered severe hypercalcaemia from a functioning parathyroid cyst: the limitations of intraoperative parathyroid hormone (IOPTH) monitoring

JC Nogues, R Cox, C Mulcahy, D Benito… - … Case Reports CP, 2021 - casereports.bmj.com
Parathyroid cysts (PCs) are rare pathologies and are typically non-functional (do not secrete
parathyroid hormone (PTH)). The aetiology of PCs is highly debated, and management is …

[PDF][PDF] Repli-seq: genome-wide analysis of replication timing by next-generation sequencing

…, J Sima, JC Rivera-Mulia, CT García, C Nogues… - 2017 - researchgate.net
Cycling cells duplicate their DNA content during S phase, following a defined program called
replication timing (RT). Early and late replicating regions differ in terms of mutation rates, …

Phylogeny and the prediction of tree functional diversity across novel continental settings

…, J Kollmann, D Nogués‐Bravo… - Global Ecology and …, 2017 - Wiley Online Library
Aim Mapping the distribution and diversity of plant functional traits is critical for projecting
future changes to vegetation under global change. Maps of plant functional traits, however, are …

Permeability evolution due to dissolution and precipitation of carbonates using reactive transport modeling in pore networks

JP Nogues, JP Fitts, MA Celia… - Water Resources …, 2013 - Wiley Online Library
A reactive transport model was developed to simulate reaction of carbonates within a pore
network for the high‐pressure CO 2 ‐acidified conditions relevant to geological carbon …