Tissue factor (TF) circulates in plasma, largely on monocyte/macrophage-derived microvesicles
that can bind activated platelets through a mechanism involving P-selectin glycoprotein …

Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen
receptor–modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in …

Microvascular networks support metabolic activity and define microenvironmental conditions
within tissues in health and pathology. Recapitulation of functional microvascular structures …

A common assumption in the academic literature and in the supervision of banking systems
is that franchise value plays a key role in limiting bank risk-taking. As market power is the …

Publisher Summary Forecasts are of great importance and are widely used in economics
and finance. Quite simply, good forecasts lead to good decisions. The importance of forecast …

IN 1948, BERNARD AND SOULIER described a young male patient with a severe bleeding
disorder that was characterized by a prolonged bleeding time, thrombocytopenia, and …

Colorectal cancer is the second leading cause of cancer death in developed countries.
There is a need for better preventive strategies to improve the outcome of this disease. The …

Inflammation and thrombosis are two responses that are linked through a number of
mechanisms, one of them being the complement system. Various proteins of the complement …

Although dependence in effect sizes is ubiquitous, commonly used meta-analytic methods
assume independent effect sizes. We describe and illustrate three-level extensions of a mixed …

Since 1998, US commercial banks with significant trading activities have been required to
hold capital against their defined market risk exposure. Under the “internal models” approach …