The United States is experiencing an epidemic of opioid-related deaths. Naloxone, the drug
of choice for reversing acute opioid overdose, is not routinely prescribed for outpatient use. …

Novel tumor-targeting drug conjugates, BLT-F 2 (1) and BLT-SF 6 (2), bearing a fluorotaxoid
as the warhead, a mechanism-based self-immolative disulfide linker, and biotin as the tumor…

The phenotypic consequences of expression quantitative trait loci (eQTLs) are presumably
due to their effects on protein expression levels. Yet the impact of genetic variation, including …

Five Sustainable Development Goals (SDGs) set targets that relate to the reduction of health
inequalities nationally and worldwide. These targets are poverty reduction, health and …

Vaccines have had broad medical impact, but existing vaccine technologies and production
methods are limited in their ability to respond rapidly to evolving and emerging pathogens, …

Changes in gene regulation have likely played an important role in the evolution of primates.
Differences in messenger RNA (mRNA) expression levels across primates have often been …

Despite extensive commercial and regulatory interventions, food spoilage and contamination
continue to impose massive ramifications on human health and the global economy. …

Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that
involve inflammation, such as chronic asthma and obstructive pulmonary disease. To this end, …

Dysfunctional endothelial cells contribute to the pathophysiology of many diseases, including
vascular disease, stroke, hypertension, atherosclerosis, organ failure, diabetes, retinopathy…

Rice husk (RH) is an agricultural waste, and easily available in rice growing areas. The husk
is mostly burnt as a way of getting rid of it. The ash obtained after burning or calcination …