Activation of Transcription Factor Nrf-2 and Its Downstream Targets in Response to Moloney Murine Leukemia Virus ts1-Induced Thiol Depletion and Oxidative Stress …

…, X Kuang, N Liu, VL Scofield, JR Voorhees… - Journal of …, 2004 - Am Soc Microbiol
The neuroimmunodegenerative syndrome that develops in mice infected with ts1, a mutant
of Moloney murine leukemia virus, resembles human AIDS. Both ts1 and human …

Mutational analysis of 206 families with cavernous malformations

…, ML DiLuna, D Shin, F Niazi, JR Voorhees… - Journal of …, 2003 - thejns.org
Object. A gene contributing to the autosomal-dominant cerebral cavernous malformation (CCM)
phenotype, KRIT1 (an acronym for Krev Interaction Trapped 1 ), has been identified …

Battling blood loss in neurosurgery: Harvey Cushing's embrace of electrosurgery

JR Voorhees, AA Cohen-Gadol, ER Laws… - Journal of …, 2005 - thejns.org
✓ For his pioneering spirit, definitive work, and unparalleled devotion to conquering
neurosurgery's toughest obstacles, Harvey Williams Cushing inarguably has earned the title, “The …

Discussing physician-assisted dying: physicians' experiences in the United States and the Netherlands

JR Voorhees, JAC Rietjens, A Van Der Heide… - The …, 2014 - academic.oup.com
Purpose of the Study: This study aims to further our understanding of the experiences of
physicians when discussing physician-assisted dying (PAD) within the context of doctor–patient …

Approaches to suffering at the end of life: the use of sedation in the USA and Netherlands

JAC Rietjens, JR Voorhees, A Van Der Heide… - Journal of medical …, 2014 - jme.bmj.com
Background Studies describing physicians’ experiences with sedation at the end of life are
indispensible for informed palliative care practice, but they are scarce. We describe the …

A small percentage of family physicians report time devoted to research

JR Voorhees, IM Xierali, AW Bazemore… - The Journal of the …, 2013 - Am Board Family Med
Despite calls by family medicine organizations to build research capacity within the
discipline, few family physicians report research activity. Policy that supports efforts in family …

Krev1 Interaction Trapped—1/Cerebral Cavernous Malformation—1 protein expression during early angiogenesis

…, UA Kayisli, NM Amankulor, JR Voorhees… - Journal of …, 2004 - thejns.org
Object. Molecular genetic studies of cerebral cavernous malformation (CCM) have identified
three loci, CCM1–3, that can lead to CCM when mutated. Examination of the CCM1 locus …

Early evolution of neurological surgery: conquering increased intracranial pressure, infection, and blood loss

JR Voorhees, AA Cohen-Gadol, DD Spencer - Neurosurgical Focus, 2005 - thejns.org
At the end of the 19th century, the early evolution of the specialty of neurological surgery
was restricted by complications related to infection, increased intracranial pressure, and …

William S. Halsted and Harvey W. Cushing: reflections on their complex association: Historical vignette

JR Voorhees, RS Tubbs, B Nahed… - Journal of …, 2009 - thejns.org
William Stewart Halsted, the father of modern surgery, and Harvey Williams Cushing, the father
of neurosurgery, are remembered for their countless innovations and contributions to the …

Structural basis of the translational elongation cycle

RM Voorhees, V Ramakrishnan - Annual review of biochemistry, 2013 - annualreviews.org
The sequential addition of amino acids to a growing polypeptide chain is carried out by the
ribosome in a complicated multistep process called the elongation cycle. It involves accurate …