Successful trial of practice facilitation for plan, do, study, act quality improvement

KF Sutton, EL Richman, JR Rees… - The Journal of the …, 2021 - Am Board Family Med
Background: Practice facilitation (PF) is a promising but relatively new intervention supporting
data-driven practice change. There is a need to better detail research-based facilitation …

New layered double hydroxides by prepared by the intercalation of gibbsite

JR Rees, CS Burden, AM Fogg - Journal of Solid State Chemistry, 2015 - Elsevier
New layered double hydroxides (LDHs) with the composition [MAl 4 (OH) 12 ]Cl 2 ·1.5H 2 O
(M=Co, Ni) have been prepared by reacting gibbsite, γ-Al(OH) 3 , with the appropriate …

[HTML][HTML] Implementing practice facilitation in research: how facilitators spend their time guiding practices to improve blood pressure control

KF Sutton, EL Richman, JR Rees… - Implementation Science …, 2023 - Springer
Background Practice facilitators (PFs) coach practices through quality improvement (QI)
initiatives aimed at enhancing patient outcomes and operational efficiencies. Practice facilitation …

A phase 1 dose-escalation trial of radiation therapy and concurrent cisplatin for stage II and III triple-negative breast cancer

JR Bellon, YH Chen, R Rees, AG Taghian… - International Journal of …, 2021 - Elsevier
Purpose Patients with triple-negative breast cancer (TNBC) experience higher local-regional
recurrence rates than those with luminal or HER2-positive tumors. This prospective, phase …

Discovery and preclinical characterization of AMG 650, a first-in-class inhibitor of kinesin KIF18A motor protein with potent activity against chromosomally unstable …

…, S Ghimire-Rijal, Y Hao, CP Mohr, X Yu, MG Rees… - Cancer Research, 2023 - AACR
Chromosomal instability (CIN) is a hallmark of human cancers and is caused by persistent
errors in chromosome segregation during mitosis. Aggressive types of human cancer such as …

[HTML][HTML] Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

…, PJ Beltran, J Canon, AS Boghossian, MG Rees… - Nature Cancer, 2024 - nature.com
Chromosomal instability (CIN) is a hallmark of cancer, caused by persistent errors in chromosome
segregation during mitosis. Aggressive cancers like high-grade serous ovarian cancer …

Abstract B177: The discovery and preclinical characterization of AMG 193, a first-in-class MTA-cooperative PRMT5 inhibitor with broad activity against MTAP-null …

…, J Moriguchi, H Tan, F Xie, F Aeffner, MG Rees… - Molecular Cancer …, 2023 - AACR
Homozygous deletion of the methylthioadenosine phosphorylase (MTAP) gene occurs in
approximately 15% of all cancers due to its proximity to the commonly deleted tumor …

Abstract LB202: Discovery and preclinical characterization of novel small molecule inhibitors of kinesin KIF18A motor protein with potent activity against …

…, JD McCarter, UP Dahal, AS Boghossian, MG Rees… - Cancer Research, 2022 - AACR
KIF18A is a mitotic kinesin that localizes to the plus-end tips of kinetochore microtubule (MT)
spindle fibers during metaphase, where it regulates chromosome alignment, and promotes …

Prioritizing health care strategies to reduce childhood mortality

…, S El Arifeen, EAS Whitney, K Seib, CA Rees… - JAMA network …, 2022 - jamanetwork.com
Importance Although child mortality trends have decreased worldwide, deaths among
children younger than 5 years of age remain high and disproportionately circumscribed to sub-…

[HTML][HTML] Supramolecular clustering of the cardiac sodium channel Nav1. 5 in HEK293F cells, with and without the auxiliary β3‐subunit

SC Salvage, JS Rees, A McStea, M Hirsch… - The FASEB …, 2020 - ncbi.nlm.nih.gov
Voltage‐gated sodium channels comprise an ion‐selective α‐subunit and one or more
associated β‐subunits. The β3‐subunit (encoded by the SCN3B gene) is an important …