User profiles for James E. Galvin

James Galvin

Professor of Neurology, University of Miami Miller School of Medicine
Verified email at miami.edu
Cited by 30616

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

…, K Yurko-Mauro, EB Nelson, C Van Dyck, JE Galvin… - Jama, 2010 - jamanetwork.com
Context Docosahexaenoic acid (DHA) is the most abundant long-chain polyunsaturated fatty
acid in the brain. Epidemiological studies suggest that consumption of DHA is associated …

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

P Tu, JE Galvin, M Baba, B Giasson… - Annals of …, 1998 - Wiley Online Library
Recently, α‐synuclein was shown to be a structural component of the filaments in Lewy bodies
(LBs) of Parkinson's disease (PD), dementia with LBs (DLB) as well as the LB variant of …

Synucleinopathies: clinical and pathological implications

JE Galvin, VMY Lee, JQ Trojanowski - Archives of neurology, 2001 - jamanetwork.com
The synucleinopathies are a diverse group of neurodegenerative disorders that share a
common pathologic lesion composed of aggregates of insoluble α-synuclein protein in …

Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains α-, β-, and γ-synuclein

JE Galvin, K Uryu, VMY Lee… - Proceedings of the …, 1999 - National Acad Sciences
Pathogenic α-synuclein (αS) gene mutations occur in rare familial Parkinson’s disease (PD)
kindreds, and wild-type αS is a major component of Lewy bodies (LBs) in sporadic PD, …

Validity and reliability of the AD8 informant interview in dementia

JE Galvin, CM Roe, C Xiong, JC Morris - Neurology, 2006 - AAN Enterprises
Objective: To establish the validity, reliability, and discriminative properties of the AD8, a
brief informant interview to detect dementia, in a clinic sample. Methods: We evaluated 255 …

Research criteria for the diagnosis of prodromal dementia with Lewy bodies

…, C Ballard, L Bonanni, P Donaghy, M Emre, JE Galvin… - Neurology, 2020 - AAN Enterprises
The prodromal phase of dementia with Lewy bodies (DLB) includes (1) mild cognitive
impairment (MCI), (2) delirium-onset, and (3) psychiatric-onset presentations. The purpose of our …

Phase 2 safety trial targeting amyloid β production with a γ-secretase inhibitor in Alzheimer disease

…, CM Clark, RA Dean, MR Farlow, JE Galvin… - Archives of …, 2008 - jamanetwork.com
… Optional DNA testing for apolipoprotein E subtype was performed. … -Mental State Examination
[MMSE] scores), apolipoprotein E ε4 distribution, and acetylcholine esterase inhibitor and …

Distinguishing Alzheimer's disease from other major forms of dementia

S Karantzoulis, JE Galvin - Expert review of neurotherapeutics, 2011 - Taylor & Francis
Alzheimer’s disease (AD) is the most common and most studied cause of dementia. Significant
advances have been made since the first set of clinical criteria for AD were put forth in …

Longitudinal study of the transition from healthy aging to Alzheimer disease

…, M Storandt, JC Morris, JE Galvin - Archives of …, 2009 - jamanetwork.com
… Drs Johnson and Galvin take full responsibility for the integrity of the data and the accuracy
… Drafting of the manuscript: Johnson, Storandt, and Galvin. Critical revision of the manuscript …

Curcumin inhibits aggregation of α-synuclein

…, J Strider, WC Nolan, SX Yan, JE Galvin - Acta neuropathologica, 2008 - Springer
Aggregation of amyloid-beta protein (Aβ) is a key pathogenic event in Alzheimer’s disease (AD).
Curcumin, a constituent of the Indian spice Turmeric is structurally similar to Congo Red …