Long-term central venous catheters (CVCs) are important instruments in the care of patients
with chronic illnesses, but catheter occlusions and catheter-related thromboses are common …

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Background Cure rates among children with brain tumors differ between low-income and
high-income countries. To evaluate causes of these differences, we analyzed aspects of care …

Thrombosis and Thrombocytopenia from Adenovirus Infection VITT is caused by antibodies
to PF4 that recognize the heparin-binding site. Thrombocytopenia and thrombosis …

Introduction: Although most patients with rare diseases like sickle cell disease (SCD) are
treated in the primary care setting, primary care physicians may find it challenging to keep …

The importance of protecting brain function for people with sickle cell disease (SCD) cannot
be overstated. SCD is associated with multiple cerebrovascular complications that threaten …

Objective and importance Homozygous Southeast Asian alpha-thalassemia mutation (--
SEA /-- SEA ) results in deletion of all alpha-globin genes (alpha(0)-thalassemia). Since all …

Patients with sickle cell disease (SCD) who identify as transgender pose a management
challenge. Standard care for transgender patients is cross-sex hormone therapy (CSHT), but …

Background Reducing variation in transfusion practices can prevent unwarranted transfusions,
an outcome that improves quality of care and patient safety, while lowering costs and …

Introduction: Transition from pediatric to adult care for emerging adults with sickle cell disease
(SCD) has been challenging due to limited availability of experienced adult providers and …