Heart rate variability: origins, methods, and interpretive caveats

GG Berntson, J Thomas Bigger Jr… - …, 1997 - Wiley Online Library
Components of heart rate variability have attracted considerable attention in psychology
and medicine and have become important dependent measures in psychophysiology and …

Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention …

JH Lichtman, JT Bigger Jr, JA Blumenthal… - Circulation, 2008 - Am Heart Assoc
Depression is commonly present in patients with coronary heart disease (CHD) and is
independently associated with increased cardiovascular morbidity and mortality. Screening tests …

Heart rate variability: measurement and clinical utility

…, PK Stein, JT Bigger Jr - Annals of Noninvasive …, 2005 - Wiley Online Library
Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes,
and other genetic and environmental factors that are mediated through the autonomic …

Decreased heart rate variability and its association with increased mortality after acute myocardial infarction

RE Kleiger, JP Miller, JT Bigger Jr, AJ Moss - The American journal of …, 1987 - Elsevier
A high degree of heart rate (HR) variability is found in compensated hearts with good function,
whereas HR variability can be decreased with severe coronary artery disease, congestive …

Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction

MT La Rovere, JT Bigger, FI Marcus, A Mortara… - The Lancet, 1998 - thelancet.com
Background Experimental evidence suggests that autonomic markers such as heart-rate
variability and baroreflex sensitivity (BRS) may contribute to post-infarction risk stratification. …

Frequency domain measures of heart period variability and mortality after myocardial infarction.

JT Bigger Jr, JL Fleiss, RC Steinman, LM Rolnitzky… - Circulation, 1992 - Am Heart Assoc
BACKGROUND We studied 715 patients 2 weeks after myocardial infarction to establish the
associations between six frequency domain measures of heart period variability (HPV) and …

Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North …

AJ Camm, M Malik, JT Bigger, G Breithardt, S Cerutti… - Circulation, 1996 - air.unimi.it
Heart rate variability: standards of measurement, physiological interpretation and clinical use.
Task Force of the European Society of Cardiology and the North American Society of Pacing …

Sertraline treatment of major depression in patients with acute MI or unstable angina

…, RM Califf, K Swedberg, P Schwartz, JT Bigger Jr… - Jama, 2002 - jamanetwork.com
ContextMajor depressive disorder (MDD) occurs in 15% to 23% of patients with acute
coronary syndromes and constitutes an independent risk factor for morbidity and mortality. …

The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction.

JT Bigger Jr, JL Fleiss, R Kleiger, JP Miller… - Circulation, 1984 - Am Heart Assoc
We examined the relationships among ventricular arrhythmias, left ventricular dysfunction,
and mortality after the occurrence of myocardial infarction in 766 patients who enrolled in a …

Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction

…, R Schneider, K Ulm, L Rolnitzky, AJ Camm, JT Bigger… - The Lancet, 1999 - thelancet.com
Background Identification of high-risk patients after acute myocardial infarction is essential for
successful prophylactic therapy. The predictive accuracy of currently used risk predictors is …