Cognitive change affecting patients after anaesthesia and surgery has been recognised for
more than 100 yr. Research into cognitive change after anaesthesia and surgery accelerated …

Importance Delirium is defined as an acute disorder of attention and cognition. It is a common,
serious, and often fatal condition among older patients. Although often underrecognized, …

… Delirium is usually due to multifactorial causes and diagnostic evaluation should be
targeted based on patient’s history and physical examination; cognitive impairment is an …

Objectives Individuals with mild cognitive impairment (MCI) are at high risk of developing
dementia and/or Alzheimer disease (AD). Among persons with MCI, depression and anxiety …

Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging
population and society as a whole. With the numbers of people with ADRDs predicted to rise …

Purpose Undernutrition is often suspected in patients when serum albumin or prealbumin
levels are low. We asked whether these measures are indeed low in undernourished people if …

Background: Delirium is common in hospitalized patients and is associated with worse
outcomes. Antipsychotics are commonly used; however, the associated benefits and harms are …

Although a causal association remains to be determined, epidemiologic evidence suggests
an association between hearing loss and increased risk of dementia. If we determine the …

Objective Systematically identify preoperative clinical risk factors for incident postoperative
delirium in individuals undergoing hip fracture repair in order to guide clinicians in identifying …

Although loss of TAR DNA-binding protein 43 kDa (TDP-43) splicing repression is well
documented in postmortem tissues of amyotrophic lateral sclerosis (ALS) and frontotemporal …