MRI-based cartilage compositional analysis shows biochemical and microstructural
changes at early stages of osteoarthritis before changes become visible with structural MRI …

Until recently there has been little evidence available to validate any method by which to
make an accurate diagnosis of an osteoporotic vertebral fractures (OVFs) from plain …

Objectives To evaluate the impact of total knee replacement on quality of life in people with
knee osteoarthritis and to estimate associated differences in lifetime costs and quality …

OBJECTIVE We aimed to assess whether individuals with type 2 diabetes (T2D) have increased
risk of vertebral fractures (VFs) and to estimate nonvertebral fracture and mortality risk …

Inflammation is the hallmark and main driver of both inflammatory and infectious joint diseases
1, 2 that will lead to rapid destruction of the joint structures if appropriate diagnosis and …

Objective To examine the proportion of isolated patellofemoral osteoarthritis (PFOA) compared
to tibiofemoral osteoarthritis (TFOA) in middle-aged participants with early osteoarthritis (…

Background With accumulating knowledge on osteoarthritis development, the next step is to
focus on possibilities for primary prevention. Methods In a 2 × 2 factorial design, the effects …

Existing quantitative imaging biomarkers (QIBs) are associated with known biological tissue
characteristics and follow a well-understood path of technical, biological and clinical …

Objective A cam-type deformity drastically increases the risk of hip osteoarthritis (OA). Since
this type of skeletal anomaly is more prevalent among young active adults, it is hypothesized …

Active joint inflammation is a key feature in rheumatoid arthritis (RA). Treatment guidelines
for RA, 1 including ‘Treatto-Target’strategies, 2 stress the importance of abrogation of …