… The first set of primers (black bars, MYC-C) showed a bell shaped optimisation pattern where
the intermediate concentrations were optimum and giving ratio of target to reference close …

The formation of clusters of altered axons and dendrites surrounding extracellular deposits
of amyloid filaments (neuritic plaques) is a major feature of the human brain in both aging …

Background: Many smartphone applications (apps) for weight loss are available, but little is
known about their effectiveness. Objective: To evaluate the effect of introducing primary care …

We leveraged the largely untapped resource of electronic health record data to address critical
clinical and epidemiological questions about Coronavirus Disease 2019 (COVID-19). To …

Objective Alert fatigue represents a common problem associated with the use of clinical
decision support systems in electronic health records (EHR). This problem is particularly …

Joubert syndrome related disorders (JSRDs) have broad but variable phenotypic overlap
with other ciliopathies. The molecular etiology of this overlap is unclear but probably arises …

Importance Chronic kidney disease (CKD) is serious and common, yet recognition and
public health responses are limited. Objective To describe clinical features of, prevalence of, …

Background The appropriate dose of aspirin to lower the risk of death, myocardial infarction,
and stroke and to minimize major bleeding in patients with established atherosclerotic …

Purpose To examine the prevalence of comorbid chronic pain among patients with opioid
use disorder (OUD) and to compare other comorbidities (substance use disorder (SUD), …

Objectives: Elevated mortality has been observed among individuals with opioid use disorder
(OUD) treated in addiction specialty clinics or programs. Information about OUD patients in …