5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
Loss of heterozygosity on chromosome 9p21 is one of the most frequent genetic alterations
identified in human cancer. The rate of point mutations of p16, a candidate suppressor gene …
identified in human cancer. The rate of point mutations of p16, a candidate suppressor gene …
The Clinician-Administered PTSD Scale for DSM–5 (CAPS-5): Development and initial psychometric evaluation in military veterans.
The Clinician-Administered PTSD Scale (CAPS) is an extensively validated and widely used
structured diagnostic interview for posttraumatic stress disorder (PTSD). The CAPS was …
structured diagnostic interview for posttraumatic stress disorder (PTSD). The CAPS was …
Replication fork stability confers chemoresistance in BRCA-deficient cells
Cells deficient in the Brca1 and Brca2 genes have reduced capacity to repair DNA double-strand
breaks by homologous recombination and consequently are hypersensitive to DNA-…
breaks by homologous recombination and consequently are hypersensitive to DNA-…
Psychotherapy versus pharmacotherapy for posttraumatic stress disorder: Systemic review and meta‐analyses to determine first‐line treatments
DJ Lee, CW Schnitzlein, JP Wolf… - Depression and …, 2016 - Wiley Online Library
Background Current clinical practice guidelines (CPGs) for posttraumatic stress disorder (PTSD)
offer contradictory recommendations regarding use of medications or psychotherapy as …
offer contradictory recommendations regarding use of medications or psychotherapy as …
Microsatellite alterations as clonal markers for the detection of human cancer.
Microsatellite instability has been reported to be an important feature of tumors from hereditary
nonpolyposis colorectal carcinoma (HNPCC) patients. The recent discovery of genetic …
nonpolyposis colorectal carcinoma (HNPCC) patients. The recent discovery of genetic …
Rates of p16 (MTS1) Mutations in Primary Tumors with 9p Loss
… the data of drian Merlo Cairns et al. suggest, or in a large fraction, )aniel J. Lee as our
analysis of tumor cell lines suggests? mna Schwab Resolution of this issue requires comparison …
analysis of tumor cell lines suggests? mna Schwab Resolution of this issue requires comparison …
Emotion regulation and posttraumatic stress symptoms: A meta-analysis
Emotion regulation (ER) has been identified as a critical factor in the development and
maintenance of posttraumatic stress symptoms (PTS; Bardeen, Kumpula, & Orcutt, 2013 [Journal …
maintenance of posttraumatic stress symptoms (PTS; Bardeen, Kumpula, & Orcutt, 2013 [Journal …
[HTML][HTML] 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions
The DNA damage response (DDR) protein 53BP1 protects DNA ends from excessive resection
in G1, and thereby favors repair by nonhomologous end-joining (NHEJ) as opposed to …
in G1, and thereby favors repair by nonhomologous end-joining (NHEJ) as opposed to …
[HTML][HTML] PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family
Protein arginine methylation is a common post-translational modification that has been
implicated in signal transduction, RNA processing, transcriptional regulation, and DNA repair. A …
implicated in signal transduction, RNA processing, transcriptional regulation, and DNA repair. A …
Reliable and clinically significant change in the clinician-administered PTSD Scale for DSM-5 and PTSD Checklist for DSM-5 among male veterans.
We calculated the reliable change index (RCI) and clinically significant change (CSC)
values for two widely used measures of posttraumatic stress disorder (PTSD): The Clinician-…
values for two widely used measures of posttraumatic stress disorder (PTSD): The Clinician-…