Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated
(Cas) protein systems have transformed the field of genome editing and transcriptional …

Molecular diagnosis of COVID-19 primarily relies on the detection of RNA of the SARS-CoV-2
virus, the causative infectious agent of the pandemic. Reverse transcription polymerase …

The e antigen of hepatitis B (HBeAg) is positively associated with an increased risk of
developing liver cancer and cirrhosis in chronic hepatitis B (CHB) patients. Clinical monitoring of …

Chronic hepatitis B virus (HBV) infection is a major public health problem. New treatment
approaches are needed because current treatments do not target covalently closed circular …

Highlights • Chronic HBV infection is established as a result of the persistence of the cccDNA.
• Current treatment strategies fail to cure HBV because they cannot eradicate cccDNA. • …

Eosinophilic gastroenteritis is an inflammatory disorder of the gastrointestinal tract in which
eosinophilic infiltration occurs in the gut layers. A case of subserosal eosinophilic …

The RNA-guided CRISPR/Cas9 system is a powerful genome-editing technology with
broad applications. Improving delivery efficiency and controllable activity of the CRISPR/Cas9 …

Single-cell RNA sequencing (scRNA-seq) provides rich transcriptomic information for studying
molecular events and cell heterogeneity at the single-cell level. However, it is challenging …

A 28-year-old woman with a history of asthma and recent deep venous thrombosis
presented with fever, chest pain, and peripheral eosinophilia. The patient was subsequently …

Gastric antral vascular ectasia (GAVE) syndrome, also known as watermelon stomach is a
significant cause of acute or chronic gastrointestinal blood loss in the elderly. is characterized …