Importance Acute low back pain (LBP) is highly prevalent, with a presumed favorable
prognosis; however, once chronic, LBP becomes a disabling and expensive condition. Acute to …

Background Many patients with acute low back pain (LBP) first seek care from primary care
physicians. Evidence is lacking for interventions to prevent transition to chronic LBP in this …

Importance Lumbar spinal stenosis (LSS) is the most common reason for spine surgery in
older US adults. There is an evidence gap about nonsurgical LSS treatment options. Objective …

Purpose Compare clinical outcomes of anatomic single‐bundle (SB) to anatomic double‐bundle
(DB) anterior cruciate ligament reconstruction (ACLR). It was hypothesized that …

Objective We assessed whether race or ethnicity was associated with the incidence of high-impact
chronic low back pain (cLBP) among adults consulting a primary care provider for …

Context and purpose There is an urgent need to develop vitamin D dietary recommendations
for dark-skinned populations resident at high latitude. Using data from randomised …

Background To date, no medication has slowed the progression of Parkinson’s disease (PD).
Preclinical, epidemiological, and experimental data on humans all support many benefits …

Background: Autosomal dominant polycystic kidney disease (ADPKD) commonly results in
end-stage renal disease (ESRD), yet a long-term treatment that is well tolerated is still lacking…

Objective Blunting of the sleep-related dip in blood pressure (BP) has been linked to numerous
cardiovascular outcomes including myocardial infarction. Blunting of BP dipping occurs …

Objective We sought to test the effects of different duration naps on post-nap cognitive
performance during simulated night shifts. Methods We used a randomized laboratory-based …